Vessel remodeling in the newborn: platelets fill the gap

被引:16
作者
Clyman, Ronald [1 ,2 ]
Chemtob, Sylvain [3 ,4 ,5 ]
机构
[1] Univ Calif San Francisco, Cardiovasc Res Inst, San Francisco, CA 94143 USA
[2] Univ Calif San Francisco, Dept Pediat, San Francisco, CA 94143 USA
[3] Ctr Hosp Univ Ste Justine, Dept Pediat, Montreal, PQ, Canada
[4] Ctr Hosp Univ Ste Justine, Dept Ophthalmol, Montreal, PQ, Canada
[5] Ctr Hosp Univ Ste Justine, Dept Pharmacol, Montreal, PQ, Canada
关键词
PATENT DUCTUS-ARTERIOSUS; VASA VASORUM; CLOSURE;
D O I
10.1038/nm0110-33
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
In newborn infants, permanent closure of a major blood vessel connecting the main pulmonary artery to the aorta is essential to allow adequate circulation of blood to major organs. Platelet aggregation now emerges as a crucial step in this process in newborn mice and, possibly, in preterm infants (pages 75-82).
引用
收藏
页码:33 / 35
页数:4
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