Gliomas in paediatrics. Anatomopathological analysis of 233 cases

The purpose of this paper was to analyze the anatomopathologic characteristics (location, histopathologic classification and gradation) of 233 Central Nervous System gliomas registered in the National Pediatric Neurosurgery Reference Center (Cuba), and to compare these results with other series from the literature. Results: Gliomas represented 49,6% of the total nervous system turners diagnosed while collecting this series. The histopathologic gradation of the gliomas was: Grade 1: 71, Grade 11: 84, grades 111: 64 and grade IV: 6. The histopathologic classification was: 107 grade I-II Astrocytoma; 51 grade III-IV Astrocytoma; 37 grade 141 Ependymoma; 21 grade III Ependymoma; 7 grade 11 Oligodendroglioma; 3 grade 11 Oligoastrocytoma and I grade III Oligoastrocytoma. The locations of the gliomas were: 222 intracranial (127 supratentorial y 95 infratentorial) and I I in the spinal cord. Male to female ratio was 1.3:1. Conclusions: Supratentorial gliomas were more frequent, different from other reported series. Pilocytic Astrocytoma was the more frequent glioma in this study.