MACiE (Mechanism, Annotation and Classification in Enzymes): novel tools for searching catalytic mechanisms

被引:55
作者
Holliday, Gemma L.
Almonacid, Daniel E.
Bartlett, Gail J.
O'Boyle, Noel M.
Torrance, James W.
Murray-Rust, Peter
Mitchell, John B. O.
Thornton, Janet M.
机构
[1] EMBL EBI, Cambridge CB10 1SD, England
[2] Univ Cambridge, Dept Chem, Unilever Ctr Mol Sci Informat, Cambridge CB2 1EW, England
基金
英国生物技术与生命科学研究理事会;
关键词
D O I
10.1093/nar/gkl774
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
MACiE (Mechanism, Annotation and Classification in Enzymes) is a database of enzyme reaction mechanisms, and is publicly available as a web-based data resource. This paper presents the first release of a web-based search tool to explore enzyme reaction mechanisms in MACiE. We also present Version 2 of MACiE, which doubles the dataset available (from Version 1). MACiE can be accessed from http://www.ebi.ac.uk/thornton-srv/databases/MACIE/.
引用
收藏
页码:D515 / D520
页数:6
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