Analysis on the emission and potential application of Cherenkov radiation in boron neutron capture therapy: A Monte Carlo simulation study

被引：7

作者：

Shu, Di-Yun ^{[1
]}

Geng, Chang-Ran ^{[1
]}

Tang, Xiao-Bin ^{[1
,2
]}

Gong, Chun-Hui ^{[1
]}

Shao, Wen-Cheng ^{[1
]}

Ai, Yao ^{[1
]}

机构：

[1] Nanjing Univ Aeronaut & Astronaut, Dept Nucl Sci & Engn, 29 Yudao St, Nanjing 210016, Jiangsu, Peoples R China

[2] Collaborat Innovat Ctr Radiat Med Jiangsu Higher, 29 Yudao St, Nanjing 210016, Jiangsu, Peoples R China

来源：

APPLIED RADIATION AND ISOTOPES | 2018年 / 137卷

基金：

中国国家自然科学基金;

关键词：

Cherenkov radiation; Boron neutron capture therapy; Boron concentration; Geant4; GLIOBLASTOMA-MULTIFORME; EPITHERMAL NEUTRON; BEAM; BNCT; DOSIMETRY; BSA;

D O I：

10.1016/j.apradiso.2018.04.012

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

This paper was aimed to explore the physics of Cherenkov radiation and its potential application in boron neutron capture therapy (BNCT). The Monte Carlo toolkit Geant4 was used to simulate the interaction between the epithermal neutron beam and the phantom containing boron-10. Results showed that Cherenkov photons can only be generated from secondary charged particles of gamma rays in BNCT, in which the 2.223 MeV prompt gamma rays are the main contributor. The number of Cherenkov photons per unit mass generated in the measurement region decreases linearly with the increase of boron concentration in both water and tissue phantom. The work presented the fundamental basis for applications of Cherenkov radiation in BNCT.

引用

页码：219 / 224

页数：6

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