Conducting polymer and its composite materials based electrochemical sensor for Nicotinamide Adenine Dinucleotide (NADH)

被引:96
作者
Omar, Fatin Saiha [1 ]
Duraisamy, Navaneethan [1 ]
Ramesh, K. [1 ]
Ramesh, S. [1 ]
机构
[1] Univ Malaya, Fac Sci, Dept Phys, Ctr Ion Univ Malaya, Kuala Lumpur 50603, Malaysia
关键词
NADH; Conducting polymer; Composite; Electrochemistry; PRINTED CARBON ELECTRODE; ELECTROCATALYTIC OXIDATION; VOLTAMMETRIC OXIDATION; POLY(NEUTRAL RED); HIGH-PERFORMANCE; ASCORBIC-ACID; FILM; NANOTUBES; NANOCOMPOSITE; MEDIATOR;
D O I
10.1016/j.bios.2016.01.013
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
Nicotinamide Adenine Dinucleotide (NADH) is an important coenzyme in the human body that participates in many metabolic reactions. The impact of abnormal concentrations of NADH significantly causes different diseases in human body. Electrochemical detection of NADH using bare electrode is a challenging task especially in the presence of main electroactive interferences such as ascorbic acid (AA), uric acid (UA) and dopamine (DA). Modified electrodes have been widely explored to overcome the problems of poor sensitivity and selectivity occurred from bare electrodes. This review gives an overview on the progress of using conducting polymers, polyelectrolyte and its composites (co-polymer, carbonaceous, metal, metal oxide and clay) based modified electrodes for the sensing of NADH. In addition, developments on the fabrication of numerous conducting polymer composites based modified electrodes are clearly described. (C) 2016 Elsevier B.V. All rights reserved.
引用
收藏
页码:763 / 775
页数:13
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