Diarrhea caused by viruses in transplant recipients

被引:35
作者
Lee, L. Y. [1 ,2 ]
Ison, M. G. [1 ,2 ,3 ,4 ]
机构
[1] Northwestern Univ, Feinberg Sch Med, Dept Med, Chicago, IL 60611 USA
[2] Northwestern Univ, Feinberg Sch Med, Northwestern Univ Transplant Outcomes Res Collabo, Chicago, IL 60611 USA
[3] Northwestern Univ, Feinberg Sch Med, Div Infect Dis, Chicago, IL 60611 USA
[4] Northwestern Univ, Feinberg Sch Med, Div Organ Transplantat, Chicago, IL 60611 USA
关键词
diarrhea; solid organ transplantation; norovirus; rotavirus; adenovirus; cytomegalovirus; SMALL-BOWEL TRANSPLANTATION; SOLID-ORGAN TRANSPLANTATION; CHRONIC NOROVIRUS INFECTION; POLYMERASE-CHAIN-REACTION; HEMATOPOIETIC STEM-CELL; TRANSCRIPTION-PCR ASSAY; BLOOD GROUP ANTIGENS; GROUP-C ROTAVIRUS; CYTOMEGALOVIRUS-INFECTION; NORWALK VIRUS;
D O I
10.1111/tid.12212
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Diarrhea is a common complication after solid organ transplantation, and viruses are emerging as important but underestimated causative agents. Viral infections in solid organ transplant (SOT) recipients can result in severe and prolonged diarrhea with significant patient morbidity and graft complications. Cytomegalovirus remains the most common of the viruses to cause diarrhea, but other viruses are being increasingly recognized, including norovirus, rotavirus, and adenovirus. This article reviews the epidemiology, clinical presentation, diagnosis, management, and outcomes of these viral causes of diarrhea in SOT patients.
引用
收藏
页码:347 / 358
页数:12
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