Caffeic Acid Phenethyl Ester and Therapeutic Potentials

被引：171
作者：
Murtaza, Ghulam [1 ]
Karim, Sabiha [2 ]
Akram, Muhammad Rouf [3 ]
Khan, Shujaat Ali [1 ]
Azhar, Saira [1 ]
Mumtaz, Amara [4 ]
Bin Asad, Muhammad Hassham Hassan [1 ]
机构：
[1] COMSATS Inst Informat Technol, Dept Pharm, Abbottabad 22060, Pakistan
[2] Univ Punjab, Univ Coll Pharm, Lahore 54000, Pakistan
[3] Univ Sargodha, Dept Pharm, Sargodha 40100, Pakistan
[4] COMSATS Inst Informat Technol, Dept Chem, Abbottabad 22060, Pakistan
来源：
BIOMED RESEARCH INTERNATIONAL | 2014年 / 2014卷
关键词：
FACTOR-KAPPA-B; ISCHEMIA-REPERFUSION INJURY; INDUCED OXIDATIVE STRESS; NITRIC-OXIDE; EPITHELIAL-CELLS; CANCER CELLS; SPINAL-CORD; IN-VITRO; CYCLOOXYGENASE-2; EXPRESSION; INTEGRASE INHIBITORS;
D O I：
10.1155/2014/145342
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Caffeic acid phenethyl ester (CAPE) is a bioactive compound of propolis extract. The literature search elaborates that CAPE possesses antimicrobial, antioxidant, anti-inflammatory, and cytotoxic properties. The principal objective of this review article is to sum up and critically assess the existing data about therapeutic effects of CAPE in different disorders. The findings elaborate that CAPE is a versatile therapeutically active polyphenol and an effective adjuvant of chemotherapy for enhancing therapeutic efficacy and diminishing chemotherapy-induced toxicities.
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页数：9
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