Mycobacterium haemophilum infections in heart transplant recipients:: Case report and review of the literature

被引：24

作者：

Fairhurst, RM

Kubak, BM ^{[1
]}

Pegues, DA

Moriguchi, JD

Han, KF

Haley, JC

Kobashigawa, JA

机构：

[1] Univ Calif Los Angeles, Div Infect Dis, Dept Med, Ctr Med, Los Angeles, CA 90095 USA

[2] Univ Calif Los Angeles, Div Dermatol, Dept Med, Los Angeles, CA 90095 USA

[3] Univ Calif Los Angeles, Ctr Med, Heart Transplantat Program, Los Angeles, CA 90095 USA

来源：

AMERICAN JOURNAL OF TRANSPLANTATION | 2002年 / 2卷 / 05期

关键词：

acid-fast bacilli; atypical mycobacteria; heart transplantation; Mycobacterium haemophilum; nontuberculous mycobacteria;

D O I：

10.1034/j.1600-6143.2002.20514.x

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Non-tuberculous mycobacteria are becoming increasingly important pathogens among transplant recipients. We report a case of disseminated Mycobacterium haemophilum infection in a heart transplant recipient, manifesting as cellulitis, subcutaneous nodules, septic arthritis, and pneumonitis. Our case illustrates diverse challenges in the identification and treatment of this pathogen, such as its unique culture requirements and variable antimicrobial susceptibilities. Heightened clinical suspicion is necessary to establish a timely diagnosis so that optimal treatment can be administered.

引用

收藏

页码：476 / 479

页数：4

相关论文

共 16 条

[1] ACTIVITIES OF ANTIMICROBIAL AGENTS AGAINST CLINICAL ISOLATES OF MYCOBACTERIUM-HAEMOPHILUM [J].

BERNARD, EM ;

EDWARDS, FF ;

KIEHN, TE ;

BROWN, ST ;

ARMSTRONG, D .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1993, 37 (11) :2323-2326

[2] Histologic reactions to cutaneous infections by Mycobacterium haemophilum [J].

Busam, KJ ;

Kiehn, TE ;

Salob, SP ;

Myskowski, PL .

AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 1999, 23 (11) :1379-1385

[3] INFECTIOUS COMPLICATIONS AFTER HEART-TRANSPLANTATION [J].

COOPER, DKC ;

LANZA, RP ;

OLIVER, S ;

FORDER, AA ;

ROSE, AG ;

UYS, CJ ;

NOVITZKY, D ;

BARNARD, CN .

THORAX, 1983, 38 (11) :822-828

[4] MYCOBACTERIUM-HAEMOPHILUM - AN EMERGING PATHOGEN [J].

KIEHN, TE ;

WHITE, M .

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 1994, 13 (11) :925-931

[5] MYCOBACTERIUM-HAEMOPHILUM CELLULITIS IN A HEART-TRANSPLANT RECIPIENT [J].

LEDERMAN, C ;

SPITZ, JL ;

SCULLY, B ;

SCHULMAN, LL ;

DELLALATTA, P ;

WEITZMAN, I ;

GROSSMAN, ME .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1994, 30 (05) :804-806

[6] Osteomyelitis due to Mycobacterium haemophilum in a cardiac transplant patient: Case report and analysis of interactions among clarithromycin, rifampin, and cyclosporine [J].

Plemmons, RM ;

McAllister, CK ;

Garces, MC ;

Ward, RL .

CLINICAL INFECTIOUS DISEASES, 1997, 24 (05) :995-997

[7] Mycobacterium haemophilum: Microbiology and expanding clinical and geographic spectra of disease in humans [J].

Saubolle, MA ;

Kiehn, TE ;

White, MH ;

Rudinsky, MF ;

Armstrong, D .

CLINICAL MICROBIOLOGY REVIEWS, 1996, 9 (04) :435-&

[8] Mycobacterium haemophilum in immunocompromised patients [J].

Shah, MK ;

Sebti, A ;

Kiehn, TE ;

Massarella, SA ;

Sepkowitz, KA .

CLINICAL INFECTIOUS DISEASES, 2001, 33 (03) :330-337

[9] Pyomyositis due to Mycobacterium haemophilum in a patient with polymyositis and long-term steroid use [J].

Shih, JY ;

Hsueh, PR ;

Chang, YL ;

Lin, SF ;

Teng, LJ ;

Luh, KT .

CLINICAL INFECTIOUS DISEASES, 1998, 26 (02) :505-507

[10] MYCOBACTERIUM-HAEMOPHILUM SP-NOV, A NEW PATHOGEN OF HUMANS [J].

SOMPOLINSKY, D ;

LAGZIEL, A ;

NAVEH, D ;

YANKILEVITZ, T .

INTERNATIONAL JOURNAL OF SYSTEMATIC BACTERIOLOGY, 1978, 28 (01) :67-75