Hypothyroidism After Radiotherapy for Primary Thyroid Lymphoma

被引：0

作者：

Ishibashi, Naoya ^{[1
]}

Maebayashi, Toshiya ^{[1
]}

Aizawa, Takuya ^{[1
]}

Sakaguchi, Masakuni ^{[1
]}

Abe, Osamu ^{[1
]}

Saito, Tsutomu ^{[2
]}

Kawamori, Jiro ^{[3
]}

Tanaka, Yoshiaki ^{[4
]}

机构：

[1] Nihon Univ, Sch Med, Dept Radiol, Itabashi Ku, Tokyo, Japan

[2] Sonoda Med Corp, Radiol Clin, Adachi Ku, Tokyo, Japan

[3] St Lukes Int Hosp, Dept Radiat Oncol, Chuo Ku, Tokyo, Japan

[4] Kawasaki Saiwai Hosp, Dept Radiat Oncol, Kawasaki, Kanagawa, Japan

来源：

ANTICANCER RESEARCH | 2014年 / 34卷 / 08期

关键词：

Thyroid; malignant lymphoma; radiotherapy; thyrotropin; hypothyroidism; NON-HODGKINS-LYMPHOMA; MANAGEMENT; CANCER; GLAND;

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Background: Thyroid lymphoma is rare, with no standard therapeutic protocol. Radiotherapy is often employed. Patients and Methods: Nine patients who had received radiotherapy for thyroid lymphoma in our Institute, from September 2005 to August 2013, were reviewed for hypothyroidism. The median radiation dose was 40 Gy. Thyroid-stimulating hormone (TSH) levels were measured before and after radiotherapy, and hypothyroidism was defined as a TSH level exceeding 10 mIU/l. Peak TSH was defined as the highest TSH level during the follow-up period. Results: The complete response rate was 77.8%, and the 5-year overall survival rate was 74.1%. The median time-to-peak TSH was 162.5 days after the start of radiotherapy. Hypothyroidism was diagnosed in three (37.5%) out of eight patients without thyroidectomy. Conclusion: Hypothyroidism is a frequent complication of radiotherapy for thyroid lymphoma.

引用

页码：4427 / 4431

页数：5

共 26 条

[1]

Austin JR, 1996, OTOLARYNG CLIN N AM, V29, P611

[2] RADIOTHERAPEUTIC MANAGEMENT OF PRIMARY THYROID LYMPHOMA [J].