Maternal pre-eclampsia and long-term offspring health: Is there a shadow cast?

被引：44

作者：

Goffin, Sarah M. ^{[1
]}

Derraik, Jose G. B. ^{[1
,2
,3
]}

Groom, Katie M. ^{[4
,5
]}

Cutfield, Wayne S. ^{[1
,2
]}

机构：

[1] Univ Auckland, Liggins Inst, Auckland, New Zealand

[2] Univ Auckland, Better Start Natl Sci Challenge A, Auckland, New Zealand

[3] Uppsala Univ, Dept Womens & Childrens Hlth, Uppsala, Sweden

[4] Univ Auckland, Dept Obstet & Gynaecol, Auckland, New Zealand

[5] Auckland City Hosp, Natl Womens Hlth, Auckland, New Zealand

来源：

PREGNANCY HYPERTENSION-AN INTERNATIONAL JOURNAL OF WOMENS CARDIOVASCULAR HEALTH | 2018年 / 12卷

关键词：

Pre-eclampsia; Offspring; Long-term health; Metabolism; Outcomes; 12-YEAR-OLD CHILDREN BORN; BLOOD-PRESSURE; HYPERTENSIVE DISORDERS; GESTATIONAL HYPERTENSION; PRETERM BIRTH; CARDIOVASCULAR-DISEASE; INSULIN SENSITIVITY; CHILDHOOD ASTHMA; RISK-FACTORS; PREGNANCY;

D O I：

10.1016/j.preghy.2018.02.003

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Pre-eclampsia is a common pregnancy disorder with important short-term complications for mother and baby. Evidence suggests pre-eclampsia also has implications for the mother beyond pregnancy, as well as long-term effects on offspring health. Limited research has linked pre-eclampsia with changes in offspring blood pressure, BMI, and stroke risk. Underpinning mechanisms are poorly understood, but developmental programming may be involved. Research in this area has been hindered by difficulties in defining pre-eclampsia and problems with study design. Further targeted evaluation through to adulthood is required to determine the long-term impact of pre-eclampsia on offspring disease risk and how this develops.

引用

收藏

页码：11 / 15

页数：5

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