Benzofuroxans: their synthesis, properties, and biological activity

被引：22
作者：
Chugunova, E. A. [1 ,2 ]
Gazizov, A. S. [1 ]
Burilov, A. R. [1 ]
Yusupova, L. M. [3 ]
Pudovik, M. A. [1 ]
Sinyashin, O. G. [1 ]
机构：
[1] Russian Acad Sci, Kazan Sci Ctr, Fed Res Ctr, AE Arbuzov Inst Organ & Phys Chem, 8 Ul Akad Arbuzova, Kazan 420088, Russia
[2] Kazan Fed Univ, 18 Ul Kremlyovskaya, Kazan 420008, Russia
[3] Kazan Natl Res Technol Univ, 68 Ul K Marksa, Kazan 420015, Russia
来源：
RUSSIAN CHEMICAL BULLETIN | 2019年 / 68卷 / 05期
关键词：
benzofuroxan; hybrid" compounds; tautomerism; BoultonKatritzky rearrangement; Beirut reaction; biological activity; N-OXIDE DERIVATIVES; POTENTIAL ANTITRYPANOSOMAL DRUGS; NITRIC-OXIDE; IMMUNOSUPPRESSIVE DRUGS; STRUCTURAL HYBRIDS; FURAZAN OXIDES; HETEROCYCLIC REARRANGEMENTS; QUINOXALINE 1,4-DIOXIDE; ANTIMICROBIAL ACTIVITY; BEARING BENZOFUROXAN;
D O I：
10.1007/s11172-019-2503-6
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The review provides a brief historical background for the establishment of structure of benzofuroxanes. Methods for their synthesis are summarized, and the chemical properties are described, which are splitted into two parts: reactions proceeding with a ring opening of the heterocycle, and those occuring with a participation of the isocyclic moiety. The biological activity of various representatives belonging to the benzofuroxan series is covered in details.
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页码：887 / 910
页数：24
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