Atrial fibrillation: to map or not to map?

被引：22

作者：

Yaksh, A. ^{[1
]}

Kik, C. ^{[2
]}

Knops, P. ^{[1
]}

Roos-Hesselink, J. W. ^{[3
]}

Bogers, A. J. J. C. ^{[2
]}

Zijlstra, F. ^{[4
]}

Allessie, M. ^{[5
,6
]}

de Groot, N. M. S. ^{[5
,7
]}

机构：

[1] Ba 579 Erasmus Med Ctr, Dept Cardiol, Thoraxctr, NL-3015 CE Rotterdam, Netherlands

[2] Erasmus MC, Thoraxctr, Dept Cardiothorac Surg, NL-3015 CE Rotterdam, Netherlands

[3] Ba 583A Erasmus Med Ctr, Dept Cardiol, Thoraxctr, NL-3015 CE Rotterdam, Netherlands

[4] BA 593 Erasmus Med Ctr, Dept Cardiol, Thoraxctr, NL-3015 CE Rotterdam, Netherlands

[5] BA 597 Erasmus Med Ctr, Dept Cardiol, Thoraxctr, NL-3015 CE Rotterdam, Netherlands

[6] Cardiovasc Res Inst Maastricht, Dept Physiol, Maastricht, Netherlands

[7] Erasmus MC, Ctr Thorax, Dept Cardiol, Unit Translat Electrophysiol, NL-3015 CE Rotterdam, Netherlands

来源：

NETHERLANDS HEART JOURNAL | 2014年 / 22卷 / 06期

关键词：

Atrial fibrillation; Pulmonary vein isolation; Cardiac surgery; Cardiac mapping; CATHETER ABLATION; PULMONARY VEINS; RADIOFREQUENCY ABLATION; FOCAL IMPULSE; SUBSTRATE; CURE; HYPOTHESIS; LESIONS; MODEL; TRIAL;

D O I：

10.1007/s12471-013-0481-0

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Isolation of the pulmonary veins may be an effective treatment modality for eliminating atrial fibrillation (AF) episodes but unfortunately not for all patients. When ablative therapy fails, it is assumed that AF has progressed from a trigger-driven to a substrate-mediated arrhythmia. The effect of radiofrequency ablation on persistent AF can be attributed to various mechanisms, including elimination of the trigger, modification of the arrhythmogenic substrate, interruption of crucial pathways of conduction, atrial debulking, or atrial denervation. This review discusses the possible effects of pulmonary vein isolation on the fibrillatory process and the necessity of cardiac mapping in order to comprehend the mechanisms of AF in the individual patient and to select the optimal treatment modality.

引用

页码：259 / 266

页数：8

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