Vitamin D Status in South Africa and Tuberculosis

被引：6
作者：
Abhimanyu [1 ]
Meyer, Vanessa [1 ]
Jeffery, Tamsyn Jacki [1 ]
Bornman, Liza [1 ]
机构：
[1] Univ Johannesburg, Dept Biochem, ZA-2006 Johannesburg, Gauteng, South Africa
来源：
LUNG | 2015年 / 193卷 / 06期
基金：
新加坡国家研究基金会;
关键词：
Vitamin D; 25(OH)D; Deficiency; Insufficiency; Tuberculosis; South Africa; HIGH-DOSE VITAMIN-D-3; D-RECEPTOR; PULMONARY TUBERCULOSIS; CALCIUM DEFICIENCY; BONE MASS; 25-HYDROXYVITAMIN D; SEASONAL-VARIATION; D SUPPLEMENTATION; BODY-COMPOSITION; DIETARY CALCIUM;
D O I：
10.1007/s00408-015-9789-4
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
According to the World Health Organisation South Africa has the third highest tuberculosis (TB) incidence in the world, with an estimated 60 % incident cases having both TB and HIV. The South African National Tuberculosis Association (SANTA) recognized the importance of nutrition in the prevention and management of TB by including feeding schemes in community outreach programs. Vitamin D enhances innate immunity against mycobacterial infection through the antimicrobial peptide, cathelicidin. We reviewed studies on vitamin D status, its link with TB, and potential use in therapy in multiethnic South Africa with sunlight as primary source of vitamin D. Ethnicity, season, disease state, latitude, and urbanization are critical factors to be considered in vitamin D supplementation for prevention and treatment of TB.
引用
收藏
页码：975 / 984
页数：10
相关论文
共 78 条
  • [41] Symposium 4: Vitamins, infectious and chronic disease during adulthood and aging Old wine in new bottles: vitamin D in the treatment and prevention of tuberculosis
    Martineau, Adrian R.
    [J]. PROCEEDINGS OF THE NUTRITION SOCIETY, 2012, 71 (01) : 84 - 89
  • [42] High-dose vitamin D3 during intensive-phase antimicrobial treatment of pulmonary tuberculosis: a double-blind randomised controlled trial
    Martineau, Adrian R.
    Timms, Peter M.
    Bothamley, Graham H.
    Hanifa, Yasmeen
    Islam, Kamrul
    Claxton, Alleyna P.
    Packe, Geoffrey E.
    Moore-Gillon, John C.
    Darmalingam, Mathina
    Davidson, Robert N.
    Milburn, Heather J.
    Baker, Lucy V.
    Barker, Richard D.
    Woodward, Nicholas J.
    Venton, Timothy R.
    Barnes, Korina E.
    Mullett, Christopher J.
    Coussens, Anna K.
    Rutterford, Clare M.
    Mein, Charles A.
    Davies, Geraint R.
    Wilkinson, Robert J.
    Nikolayevskyy, Vladyslav
    Drobniewski, Francis A.
    Eldridge, Sandra M.
    Griffiths, Christopher J.
    [J]. LANCET, 2011, 377 (9761) : 242 - 250
  • [43] Reciprocal seasonal variation in vitamin D status and tuberculosis notifications in Cape Town, South Africa
    Martineaua, Adrian R.
    Nhamoyebonde, Shepherd
    Onic, Tolu
    Rangaka, Molebogeng X.
    Marais, Suzaan
    Bangani, Nonzwakazi
    Tsekela, Relebohile
    Bashe, Lizl
    de Azevedo, Virginia
    Caldwell, Judy
    Venton, Timothy R.
    Timms, Peter M.
    Wilkinson, Katalin A.
    Wilkinson, Robert J.
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2011, 108 (47) : 19013 - 19017
  • [44] SUNSCREENS SUPPRESS CUTANEOUS VITAMIN-D3 SYNTHESIS
    MATSUOKA, LY
    IDE, L
    WORTSMAN, J
    MACLAUGHLIN, JA
    HOLICK, MF
    [J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1987, 64 (06) : 1165 - 1168
  • [45] Oral intake of phenylbutyrate with or without vitamin D3 upregulates the cathelicidin LL-37 in human macrophages: a dose finding study for treatment of tuberculosis
    Mily, Akhirunnesa
    Rekha, Rokeya Sultana
    Kamal, S. M. Mostafa
    Akhtar, Evana
    Sarker, Protim
    Rahim, Zeaur
    Gudmundsson, Gudmundur H.
    Agerberth, Birgitta
    Raqib, Rubhana
    [J]. BMC PULMONARY MEDICINE, 2013, 13
  • [46] Morcos M M, 1998, Boll Chim Farm, V137, P157
  • [47] Vitamin D and Calcium Status in South African Adolescents with Alcohol Use Disorders
    Naude, Celeste E.
    Carey, Paul D.
    Laubscher, Ria
    Fein, George
    Senekal, Marjanne
    [J]. NUTRIENTS, 2012, 4 (08): : 1076 - 1094
  • [48] Vitamin D status and sun exposure in Southeast Asia
    Nimitphong, Hataikarn
    Holick, Michael F.
    [J]. DERMATO-ENDOCRINOLOGY, 2013, 5 (01) : 34 - 37
  • [49] Low serum vitamin D levels and tuberculosis: a systematic review and meta-analysis
    Nnoaham, Kelechi E.
    Clarke, Aileen
    [J]. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 2008, 37 (01) : 113 - 119
  • [50] Nursyam Elly Wijaya, 2006, Acta Med Indones, V38, P3
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