Dietary sorbose ameliorates obesity and hyperglycemia in gold thioglucose-injected obese mice

被引:1
作者
Kita, K [1 ]
Kitayama, Y
Nagao, K
Hwangbo, J
Furuse, M
Okumura, J
机构
[1] Nagoya Univ, Grad Sch Bioagr Sci, Univ Farm, Lab Grassland Sci, Aichi 4700151, Japan
[2] Nagoya Univ, Grad Sch Bioagr Sci, Anim Nutr Lab, Nagoya, Aichi 4648601, Japan
[3] Natl Livestock Res Inst, Nutr Physiol Div, Suwon 441350, South Korea
[4] Kyushu Univ, Grad Sch Bioresource & Bioenvironm Sci, Div Anim & Marine Bioresources Sci, Fukuoka 8128581, Japan
关键词
sorbose; sucrose; gold-thioglucose; obesity; mice; hyperphagia; hyperglycemia; hyperinsulinemia;
D O I
10.1080/09712119.2002.9706375
中图分类号
S8 [畜牧、 动物医学、狩猎、蚕、蜂];
学科分类号
0905 ;
摘要
The influence of dietary sorbose on hyperphagia, hyperglycemia and hyperinsulinemia in gold thioglucose (GTG)-injected obese mice was examined. Body weight of GTG-injected obese mice was decreased by feeding a sorbose diet. When GTG-injected obese mice were given the diet containing sorbose, food intake was significantly lower than that of intact normal mice given a sucrose diet. The reduction in body weight of GTG-injected obese mice given dietary sorbose may be due to the decrease in food intake. Blood glucose concentration in GTG-injected obese mice was decreased by feeding the sorbose diet to the level of intact normal mice given sucrose. Feeding the sorbose diet lowered plasma insulin concentration compared to the sucrose group. It is concluded that feeding sorbose ameliorates hyperphagia, hyperglycemia and hyperinsulinemia in GTG-injected obese mice.
引用
收藏
页码:25 / 32
页数:8
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