Pyrrolizidine alkaloids from Senecio species

被引：0

作者：

da Silva, Chana de Medeiros ^{[1
]}

Bolzan, Aline Abati ^{[1
]}

Heinzmann, Berta Maria ^{[1
]}

机构：

[1] Univ Fed Santa Maria, Ctr Ciencias Saude, Dept Farm Ind, BR-97105900 Santa Maria, RS, Brazil

来源：

QUIMICA NOVA | 2006年 / 29卷 / 05期

关键词：

Senecio; pyrrolizidine alkaloids; hepatotoxicity;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Senecio species contain a large variety of secondary metabolites and many of these plants afford pyrrolizidine alkaloids. This paper is a review of the literature, describing 62 pyrrolizidine alkaloids already isolated in 62 of more than 2000 species of Senecio, distributed worldwide. The structure-activity relationships involving their toxicity are also discussed, since some Senecio species used for medicinal purposes are responsible for causing serious adverse effects.

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页码：1047 / 1053

页数：7

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