On the role of platelets in the pathogenesis of viral hepatitis

被引:11
作者
Iannacone, Matteo [1 ]
Sitia, Giovanni [2 ]
Guidotti, Luca G. [2 ,3 ]
机构
[1] Harvard Univ, Sch Med, Dept Pathol, Boston, MA 02115 USA
[2] Ist Sci San Raffaele, Dept Immunol & Infect Dis, DIBIT, I-20132 Milan, Italy
[3] Scripps Res Inst, Dept Immunol & Microbial Sci SBR 10, La Jolla, CA 92037 USA
关键词
B-VIRUS; LIVER;
D O I
10.1016/j.jhep.2009.05.005
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
引用
收藏
页码:599 / 600
页数:2
相关论文
共 8 条
[1]   Viral cross talk: Intracellular inactivation of the hepatitis B virus during an unrelated viral infection of the liver [J].
Guidotti, LG ;
Borrow, P ;
Hobbs, MV ;
Matzke, B ;
Gresser, I ;
Oldstone, MBA ;
Chisari, FV .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (10) :4589-4594
[2]   Immunobiology and pathogenesis of viral hepatitis [J].
Guidotti, Luca G. ;
Chisari, Francis V. .
ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE, 2006, 1 (01) :23-61
[3]   Platelets mediate cytotoxic T lymphocyte-induced liver damage [J].
Iannacone, M ;
Sitia, G ;
Isogawa, M ;
Marchese, P ;
Castro, MG ;
Lowenstein, PR ;
Chisari, FV ;
Ruggeri, ZM ;
Guidotti, LG .
NATURE MEDICINE, 2005, 11 (11) :1167-1169
[4]   Antiplatelet drug therapy moderates immune-mediated liver disease and inhibits viral clearance in mice infected with a replication-deficient adenovirus [J].
Iannacone, Matteo ;
Sitia, Giovanni ;
Narvaiza, Inigo ;
Ruggeri, Zaverio M. ;
Guidotti, Luca G. .
CLINICAL AND VACCINE IMMUNOLOGY, 2007, 14 (11) :1532-1535
[5]   Pathogenetic and antiviral immune responses against hepatitis B virus [J].
Iannacone, Matteo ;
Sitia, Giovanni ;
Guidotti, Luca G. .
FUTURE VIROLOGY, 2006, 1 (02) :189-196
[6]   HBV pathogenesis in animal models: Recent advances on the role of platelets [J].
Iannacone, Matteo ;
Sitia, Giovanni ;
Ruggeri, Zaverio M. ;
Guidotti, Luca G. .
JOURNAL OF HEPATOLOGY, 2007, 46 (04) :719-726
[7]   Aggravation of viral hepatitis by platelet-derived serotonin [J].
Lang, Philipp A. ;
Contaldo, Claudio ;
Georgiev, Panco ;
El-Badry, Ashraf Mohammad ;
Recher, Mike ;
Kurrer, Michael ;
Cervantes-Barragan, Luisa ;
Ludewig, Burkhard ;
Calzascia, Thomas ;
Bolinger, Beatrice ;
Merkler, Doron ;
Odermatt, Bernhard ;
Bader, Michael ;
Graf, Rolf ;
Clavien, Pierre-Alain ;
Hegazy, Ahmed N. ;
Loehning, Max ;
Harris, Nicola L. ;
Ohashi, Pamela S. ;
Hengartner, Hans ;
Zinkernagel, Rolf M. ;
Lang, Karl S. .
NATURE MEDICINE, 2008, 14 (07) :756-761
[8]  
Spengler Ulrich, 2009, J Hepatol, V50, P631, DOI 10.1016/j.jhep.2008.12.004