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Smoking is associated with increased resting energy expenditure in the general population: The NEO study
被引:24
|作者:
Blauw, Lisanne L.
[1
,2
]
Boon, Mariette R.
[1
,3
]
Rosendaal, Frits R.
[2
]
de Mutsert, Renee
[2
]
Gast, Karin B.
[1
,2
]
van Dijk, Ko Willems
[1
,3
,4
]
Rensen, Patrick C. N.
[1
,3
]
Dekkers, Olaf M.
[1
,2
,5
]
机构:
[1] Leiden Univ, Med Ctr, Dept Med, Div Endocrinol, NL-2300 RC Leiden, Netherlands
[2] Leiden Univ, Med Ctr, Dept Epidemiol, NL-2300 RC Leiden, Netherlands
[3] Leiden Univ, Med Ctr, Einthoven Lab Expt Vasc Med, NL-2300 RC Leiden, Netherlands
[4] Leiden Univ, Med Ctr, Dept Human Genet, NL-2300 RC Leiden, Netherlands
[5] Aarhus Univ, Dept Clin Epidemiol, DK-8000 Aarhus, Denmark
来源:
METABOLISM-CLINICAL AND EXPERIMENTAL
|
2015年
/
64卷
/
11期
关键词:
Fat free mass;
Nicotine;
Resting energy expenditure;
Smoking;
FAT-FREE MASS;
CIGARETTE-SMOKING;
METABOLIC-RATE;
BODY-COMPOSITION;
ADIPOSE-TISSUE;
NICOTINE;
QUESTIONNAIRE;
VALIDITY;
BALANCE;
WEIGHT;
D O I:
10.1016/j.metabol.2015.08.008
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
Objective. Animal studies and human studies in small selected populations have shown a positive association between nicotine smoking and resting energy expenditure (REE), but data in large cohorts are lacking. We aimed to investigate the association between smoking behavior and REE in a large, population-based study. Design. Population-based cross-sectional study. Methods. In this cross-sectional analysis of baseline measurements from the Netherlands Epidemiology of Obesity (NEO) study (n = 6673), we included participants with PEE measurement by indirect calorimety who were not using lipid or glucose lowering drugs (n = 1189). We used linear regression analysis to examine the association of smoking status (never, former, occasional, current smoker) and smoking quantity (pack years) with PEE per kilogram (kg) fat free mass (FFM) and with PEE adjusted for FFM. Models were adjusted for age, sex, ethnicity, educational level, physical activity, energy intake and body mass index (BMI). Results. Mean (standard deviation, SD) age was 55.2 (5.9) years and BMI was 26.3 (4.4) kg/m(2). 60% of the participants were women. Mean (SD) REE/FFM (kcal/day/kg FFM) Was for male never smokers 25.1 (2.0), male current smokers 26.4 (2.8), female never smokers 28.9 (2.5) and female current smokers 30.1 (3.7). After adjustment, only current smokers had a higher REE/FFM (mean difference 1.28, 95% CI 0.64, 1.92), and a higher REE adjusted for FFM (mean difference 60.3 kcal/day, 95% CI 29.1, 91.5), compared with never smokers. There was no association between pack years and REE/FFM (mean difference -0.01, 95% CI -0.06, 0.04) or REE adjusted for FFM (mean difference 0.2, 95% CI -2.4, 2.8) in current smokers. Conclusion. Current smoking is associated with a higher resting energy expenditure compared with never smoking in a large population-based cohort. (C) 2015 Elsevier Inc. All rights reserved.
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页码:1548 / 1555
页数:8
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