Construction of pyrrolo[3,2-c]quinolines -: Recent advances in the synthesis of the martinelline alkaloids

被引:43
作者
Nyerges, M [1 ]
机构
[1] Tech Univ Budapest, Dept Organ Chem Technol, Res Grp, Hungarian Acad Sci, H-1521 Budapest, Hungary
关键词
D O I
10.3987/REV-04-576
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The synthesis of pyrrolo[3,2-c]quinolines is comprehesively reviewed. Synthetic approaches to martinelline alkaloids are then considered which are based upon the endeavors in this area by three independent groups.
引用
收藏
页码:1685 / 1712
页数:28
相关论文
共 54 条
[1]   Potential antineoplastics. Synthesis and cytotoxicity of certain 4-chloro-3-(2-chloroethyl)-2-methylquinolines and related derivatives [J].
Badawey, ESAM ;
Kappe, T .
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 1997, 32 (10) :815-822
[2]   Multi-component coupling reactions:: synthesis of a guanidine containing analog of the hexahydropyrrolo[3,2-c] quinoline alkaloid martinelline [J].
Batey, RA ;
Powell, DA .
CHEMICAL COMMUNICATIONS, 2001, (22) :2362-2363
[3]   A three-component coupling protocol for the synthesis of substituted hexahydropyrrolo[3,2-c]quinolines [J].
Batey, RA ;
Simoncic, PD ;
Lin, D ;
Smyj, RP ;
Lough, AJ .
CHEMICAL COMMUNICATIONS, 1999, (07) :651-652
[4]   PSCHORR CYCLIZATION .2. FURTHER REACTIONS WITH PYRROLE DERIVATIVES [J].
BEVERIDGE, S ;
HUPPATZ, JL .
AUSTRALIAN JOURNAL OF CHEMISTRY, 1972, 25 (06) :1341-+
[5]   REVERSIBLE INHIBITORS OF THE GASTRIC (H+/K+)-ATPASE .1. 1-ARYL-4-METHYLPYRROLO[3,2-C]QUINOLINES AS CONFORMATIONALLY RESTRAINED ANALOGS OF 4-(ARYLAMINO)QUINOLINES [J].
BROWN, TH ;
IFE, RJ ;
KEELING, DJ ;
LAING, SM ;
LEACH, CA ;
PARSONS, ME ;
PRICE, CA ;
REAVILL, DR ;
WIGGALL, KJ .
JOURNAL OF MEDICINAL CHEMISTRY, 1990, 33 (02) :527-533
[6]   Study on the benzoyl-derivatives of indigo II [J].
de Diesbach, H ;
de Bie, E ;
Rubli, F .
HELVETICA CHIMICA ACTA, 1934, 17 :113-128
[7]   A synthesis of new Pyrrolo[3,2-c]quinolines [J].
Dudouit, F ;
Houssin, R ;
Hénichart, JP .
JOURNAL OF HETEROCYCLIC CHEMISTRY, 2001, 38 (03) :755-758
[8]   Asymmetric synthesis of cis-fused bicyclic pyrrolidines and pyrrolidinones via chiral polycyclic lactams [J].
Ennis, MD ;
Hoffman, RL ;
Ghazal, NB ;
Old, DW ;
Mooney, PA .
JOURNAL OF ORGANIC CHEMISTRY, 1996, 61 (17) :5813-5817
[9]   Aryl radical cyclisation onto pyrroles: a divergent synthesis of spiropyrrolidinyloxindoles and pyrroloquinolines [J].
Escolano, C ;
Jones, K .
TETRAHEDRON LETTERS, 2000, 41 (46) :8951-8955
[10]   Cyclizations of substituted benzylidene-3-alkenylamines:: Synthesis of the tricyclic core of the martinellines [J].
Frank, KE ;
Aubé, J .
JOURNAL OF ORGANIC CHEMISTRY, 2000, 65 (03) :655-666