Broad-Spectrum Antiviral Property of Polyoxometalate Localized on a Cell Surface

被引：51

作者：

Wang, Juan ^{[1
]}

Liu, Yang ^{[2
,3
]}

Xu, Kun ^{[1
]}

Qi, Yanfei ^{[1
]}

Zhong, Jun ^{[2
,3
]}

Zhang, Kai ^{[4
]}

Li, Juan ^{[1
]}

Wang, Enbo ^{[5
]}

Wu, Ziyu ^{[6
]}

Kang, Zhenhui ^{[2
,3
]}

机构：

[1] Jilin Univ, Sch Publ Hlth, Changchun 130021, Jilin, Peoples R China

[2] Soochow Univ, Jiangsu Key Lab Carbon Based Funct Mat & Devices, Inst Funct Nano & Soft Mat, Suzhou 215123, Jiangsu, Peoples R China

[3] Soochow Univ, Collaborat Innovat Ctr Suzhou Nano Sci & Technol, Suzhou 215123, Jiangsu, Peoples R China

[4] Chinese Acad Sci, Inst High Energy Phys, Beijing 100049, Peoples R China

[5] NE Normal Univ, Fac Chem, Changchun 130024, Jilin, Peoples R China

[6] Univ Sci & Technol China, Natl Synchrotron Radiat Lab, Hefei 230026, Peoples R China

来源：

ACS APPLIED MATERIALS & INTERFACES | 2014年 / 6卷 / 12期

基金：

中国国家自然科学基金;

关键词：

polyoxometalate; antiviral activity; X-ray nanotomography; HepG2; cell; nanotomography technique; HERPES-SIMPLEX-VIRUS; X-RAY TOMOGRAPHY; HETEROPOLYOXOTUNGSTATE; MECHANISM; INFECTION; PM-19;

D O I：

10.1021/am502193f

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

Cs2K4Na[SiW9Nb3O40] has broad antiviral ability including anti-Influenza A, -Influenza B, -HSV-1, -HSV-2, -HIV-1, and -HBV. A series of antivirus and/or biochemical experiments and X-ray nanotomography analysis confirm that this kind of broad-spectrum antiviral property is mainly due to its localization on the cell surface.

引用

页码：9785 / 9789

页数：5

共 31 条

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