p53 protein expression in skin with different levels of photoaging

被引：5

作者：

de Castro, Ines Alencar ^{[1
]}

Schuetz, Larissa

Capp, Edison ^{[1
]}

Cartell, Andre ^{[2
]}

Meurer, Luise ^{[2
]}

Bakos, Lucio ^{[3
]}

机构：

[1] Univ Fed Rio Grande do Sul, BR-90035077 Porto Alegre, RS, Brazil

[2] Hosp Clin Porto Alegre, Fac Med, Dept Pathol, Porto Alegre, RS, Brazil

[3] Hosp Clin Porto Alegre, Dept Dermatol, Porto Alegre, RS, Brazil

来源：

PHOTODERMATOLOGY PHOTOIMMUNOLOGY & PHOTOMEDICINE | 2009年 / 25卷 / 02期

关键词：

photoaging of skin; tumor suppressor protein p53; radiation effects; SQUAMOUS-CELL CARCINOMA; CLONES;

D O I：

10.1111/j.1600-0781.2009.00400.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

In non-melanoma skin cancer, keratinocytes show marked p53 protein expression. Considering photoaging as a background for skin cancer, p53 protein expression by immunohistochemistry was evaluated in normal skin with different levels of photoaging. The difference in p53 expression between mild and severe levels of photoaging was not statistically significant (P=0.169).

引用

页码：106 / 108

页数：3

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