p53 protein expression in skin with different levels of photoaging

被引：5
|
作者：
de Castro, Ines Alencar [1 ]
Schuetz, Larissa
Capp, Edison [1 ]
Cartell, Andre [2 ]
Meurer, Luise [2 ]
Bakos, Lucio [3 ]
机构：
[1] Univ Fed Rio Grande do Sul, BR-90035077 Porto Alegre, RS, Brazil
[2] Hosp Clin Porto Alegre, Fac Med, Dept Pathol, Porto Alegre, RS, Brazil
[3] Hosp Clin Porto Alegre, Dept Dermatol, Porto Alegre, RS, Brazil
来源：
PHOTODERMATOLOGY PHOTOIMMUNOLOGY & PHOTOMEDICINE | 2009年 / 25卷 / 02期
关键词：
photoaging of skin; tumor suppressor protein p53; radiation effects; SQUAMOUS-CELL CARCINOMA; CLONES;
D O I：
10.1111/j.1600-0781.2009.00400.x
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
In non-melanoma skin cancer, keratinocytes show marked p53 protein expression. Considering photoaging as a background for skin cancer, p53 protein expression by immunohistochemistry was evaluated in normal skin with different levels of photoaging. The difference in p53 expression between mild and severe levels of photoaging was not statistically significant (P=0.169).
引用
收藏
页码：106 / 108
页数：3
相关论文
共 50 条
  • [31] Clinical and Histopathological Correlation of p16 and p53 Expression in Oral Cancer
    Agarwal, Varun Kumar
    Sharma, Rohit
    Gahlot, G. P. S.
    Arnav, Amiy
    INDIAN JOURNAL OF SURGICAL ONCOLOGY, 2021, 12 (SUPPL 1) : 164 - 168
  • [32] Divergence between the high rate of p53 mutations in skin carcinomas and the low prevalence of anti-p53 antibodies
    C Moch
    A Moysan
    R Lubin
    P de La Salmonière
    N Soufir
    F Galisson
    C Vilmer
    E Venutolo
    F Le Pelletier
    A Janin
    N Basset-Séguin
    British Journal of Cancer, 2001, 85 : 1883 - 1886
  • [33] Expression of p53 as predictor for the development of esophageal cancer in achalasia patients
    Leeuwenburgh, I.
    Gerrits, M. M.
    Capello, A.
    van den Bogert, B.
    van Dekken, H.
    Steyerberg, E. W.
    Siersema, P. D.
    Kuipers, E. J.
    DISEASES OF THE ESOPHAGUS, 2010, 23 (06) : 506 - 511
  • [34] Investigation of HPV Infection and P53 Expression in Laryngeal Verrucous Carcinoma
    Tuncbilek, Mehmet Ali
    Calli, Caglar
    Oncel, Semih
    Pinar, Ercan
    Calli, Aylin Oergen
    TURKIYE KLINIKLERI TIP BILIMLERI DERGISI, 2010, 30 (01): : 194 - 200
  • [35] Expression of p53 and isoforms in beningn and malignant lesions of the head and neck
    Trovato, M. C.
    Ruggeri, R. M.
    Guzzo, E.
    Certo, R.
    Alibrandi, A.
    Scifo, S.
    Scardigno, M.
    Vitarelli, E.
    Arena, G.
    Gambadoro, O.
    Catalano, N.
    Bourdon, J. C.
    Galletti, B.
    Galletti, F.
    Cavallari, V.
    HISTOLOGY AND HISTOPATHOLOGY, 2017, 32 (04) : 371 - 377
  • [36] Phospholipase C ε-1 inhibits p53 expression in lung cancer
    Luo, Xue-ping
    CELL BIOCHEMISTRY AND FUNCTION, 2014, 32 (03) : 294 - 298
  • [37] p53 expression and mutation analysis of odontogenic cysts with and without dysplasia
    Cox, Darren P.
    ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY, 2012, 113 (01): : 90 - 98
  • [38] Prognostic Significance of New Immunohistochemistry Scoring of p53 Protein Expression in Cutaneous Squamous Cell Carcinoma of Mice
    Bukhari, Mulazim Hussain
    Niazi, Shahida
    Anwar, Muhammad
    Chaudhry, Naseer Ahmed
    Naeem, Samina
    RECENT ADVANCES IN CLINICAL ONCOLOGY, 2008, 1138 : 1 - 9
  • [39] THE EXPRESSION AND SIGNIFICANCE OF LIVIN. P53 AND SURVIVIN IN CUTANEOUS TUMORS
    Wan, Huiying
    JOURNAL OF DERMATOLOGY, 2014, 41 : 9 - 9
  • [40] No prognostic significance of p53 expression in esophageal squamous cell carcinoma
    Kanamoto, A
    Kato, H
    Tachimori, Y
    Watanabe, H
    Nakanishi, Y
    Kondo, H
    Yamaguchi, H
    Gotoda, T
    Muro, K
    Matsumura, Y
    JOURNAL OF SURGICAL ONCOLOGY, 1999, 72 (02) : 94 - 98
12345