Incidence and trends of childhood Type 1 diabetes worldwide 1990-1999

被引:816
作者
Bessaoud, K. [1 ]
Boudraa, G. [1 ]
Molinero de Ropolo, M. [1 ]
de Sereday, M. [1 ]
Marti, M. L. [1 ]
Moser, M. [1 ]
Lapertosa, S. [1 ]
Damiano, M. [1 ]
Verge, C. [1 ]
Howard, N. [1 ]
Schober, E. [1 ]
Jordan, O. [1 ]
Weets, I. [1 ]
Gorus, F. [1 ]
Coeckelberghs, M. [1 ]
Rooman, R. [1 ]
Van Gaal, L. [1 ]
Franco, L. J. [1 ]
Ferreira, S. R. G. [1 ]
Lisboa, H. P. K. [1 ]
Kurtz, L. A. [1 ]
Graebin, R. [1 ]
Kutzke, L. [1 ]
Rodriges, C. [1 ]
Savova, R. [1 ]
Christov, V. [1 ]
Iotova, V. [1 ]
Tzaneva, V. [1 ]
Pacaud, D. [1 ]
Toth, E. [1 ]
Tan, M. H. [1 ]
Carrasco, E. [1 ]
Perez, F. [1 ]
Ze, Y. [1 ]
Bo, Y. [1 ]
Chen, S. [1 ]
Fu, L. [1 ]
Deng, L. [1 ]
Shen, S. [1 ]
Teng, K. [1 ]
Wang, C. [1 ]
Jian, H. [1 ]
Ju, J. [1 ]
Yan, C. [1 ]
Ze, Y. [1 ]
Deng, Y. [1 ]
Li, C. [1 ]
Zhang, Y. [1 ]
Liu, Y. [1 ]
Long, X. [1 ]
机构
[1] Natl Publ Hlth Inst, SF-00300 Helsinki, Finland
关键词
epidemiology; geographical distribution; incidence; trend; Type; 1; diabetes;
D O I
10.1111/j.1464-5491.2006.01925.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Aims To examine incidence and trends of Type 1 diabetes worldwide for the period 1990-1999. Methods The incidence of Type 1 diabetes (per 100 000/year) was analysed in children aged <= 14 years from 114 populations in 112 centres in 57 countries. Trends in the incidence of Type 1 diabetes were analysed by fitting Poisson regression models to the dataset. Results A total of 43 013 cases were diagnosed in the study populations of 84 million children. The age-adjusted incidence of Type 1 diabetes among 112 centres (114 populations) varied from 0.1 per 100 000/year in China and Venezuela to 40.9 per 100 000/year in Finland. The average annual increase in incidence calculated from 103 centres was 2.8% (95% CI 2.4-3.2%). During the years 1990-1994, this increase was 2.4% (95% CI 1.3-3.4%) and during the second study period of 1995-1999 it was slightly higher at 3.4% (95% CI 2.7-4.3%). The trends estimated for continents showed statistically significant increases all over the world (4.0% in Asia, 3.2% in Europe and 5.3% in North America), except in Central America and the West Indies where the trend was a decrease of 3.6%. Only among the European populations did the trend in incidence diminish with age. Conclusions The rising incidence of Type 1 diabetes globally suggests the need for continuous monitoring of incidence by using standardized methods in order to plan or assess prevention strategies.
引用
收藏
页码:857 / 866
页数:10
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