Incidence and trends of childhood Type 1 diabetes worldwide 1990-1999

被引：832

作者：

Bessaoud, K. ^{[1
]}

Boudraa, G. ^{[1
]}

Molinero de Ropolo, M. ^{[1
]}

de Sereday, M. ^{[1
]}

Marti, M. L. ^{[1
]}

Moser, M. ^{[1
]}

Lapertosa, S. ^{[1
]}

Damiano, M. ^{[1
]}

Verge, C. ^{[1
]}

Howard, N. ^{[1
]}

Schober, E. ^{[1
]}

Jordan, O. ^{[1
]}

Weets, I. ^{[1
]}

Gorus, F. ^{[1
]}

Coeckelberghs, M. ^{[1
]}

Rooman, R. ^{[1
]}

Van Gaal, L. ^{[1
]}

Franco, L. J. ^{[1
]}

Ferreira, S. R. G. ^{[1
]}

Lisboa, H. P. K. ^{[1
]}

Kurtz, L. A. ^{[1
]}

Graebin, R. ^{[1
]}

Kutzke, L. ^{[1
]}

Rodriges, C. ^{[1
]}

Savova, R. ^{[1
]}

Christov, V. ^{[1
]}

Iotova, V. ^{[1
]}

Tzaneva, V. ^{[1
]}

Pacaud, D. ^{[1
]}

Toth, E. ^{[1
]}

Tan, M. H. ^{[1
]}

Carrasco, E. ^{[1
]}

Perez, F. ^{[1
]}

Ze, Y. ^{[1
]}

Bo, Y. ^{[1
]}

Chen, S. ^{[1
]}

Fu, L. ^{[1
]}

Deng, L. ^{[1
]}

Shen, S. ^{[1
]}

Teng, K. ^{[1
]}

Wang, C. ^{[1
]}

Jian, H. ^{[1
]}

Ju, J. ^{[1
]}

Yan, C. ^{[1
]}

Ze, Y. ^{[1
]}

Deng, Y. ^{[1
]}

Li, C. ^{[1
]}

Zhang, Y. ^{[1
]}

Liu, Y. ^{[1
]}

Long, X. ^{[1
]}

机构：

[1] Natl Publ Hlth Inst, SF-00300 Helsinki, Finland

来源：

DIABETIC MEDICINE | 2006年 / 23卷 / 08期

关键词：

epidemiology; geographical distribution; incidence; trend; Type; 1; diabetes;

D O I：

10.1111/j.1464-5491.2006.01925.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Aims To examine incidence and trends of Type 1 diabetes worldwide for the period 1990-1999. Methods The incidence of Type 1 diabetes (per 100 000/year) was analysed in children aged <= 14 years from 114 populations in 112 centres in 57 countries. Trends in the incidence of Type 1 diabetes were analysed by fitting Poisson regression models to the dataset. Results A total of 43 013 cases were diagnosed in the study populations of 84 million children. The age-adjusted incidence of Type 1 diabetes among 112 centres (114 populations) varied from 0.1 per 100 000/year in China and Venezuela to 40.9 per 100 000/year in Finland. The average annual increase in incidence calculated from 103 centres was 2.8% (95% CI 2.4-3.2%). During the years 1990-1994, this increase was 2.4% (95% CI 1.3-3.4%) and during the second study period of 1995-1999 it was slightly higher at 3.4% (95% CI 2.7-4.3%). The trends estimated for continents showed statistically significant increases all over the world (4.0% in Asia, 3.2% in Europe and 5.3% in North America), except in Central America and the West Indies where the trend was a decrease of 3.6%. Only among the European populations did the trend in incidence diminish with age. Conclusions The rising incidence of Type 1 diabetes globally suggests the need for continuous monitoring of incidence by using standardized methods in order to plan or assess prevention strategies.

引用

页码：857 / 866

页数：10

共 24 条

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