Measuring cerebral blood flow using magnetic resonance imaging techniques

被引：492
作者：
Calamante, F
Thomas, DL
Pell, GS
Wiersma, J
Turner, R
机构：
[1] UCL, Inst Neurol, Wellcome Dept Cognit Neurol, London WC1N 3BG, England
[2] UCL, Sch Med, Inst Child Hlth, RCS Unit Biophys, London W1N 8AA, England
[3] UCL, Dept Med Phys & Bioengn, London, England
来源：
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM | 1999年 / 19卷 / 07期
关键词：
cerebral blood flow; perfusion; magnetic resonance imaging; arterial spin labeling; dynamic susceptibility contrast; functional imaging;
D O I：
10.1097/00004647-199907000-00001
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Magnetic resonance imaging techniques measuring CBF have developed rapidly in the last decade, resulting in a wide range of available methods. The most successful approaches are based either on dynamic tracking of a bolus of a paramagnetic contrast agent (dynamic susceptibility contrast) or on arterial spin labeling. This review discusses their principles, possible pitfalls, and potential for absolute quantification and outlines clinical and neuroscientific applications.
引用
收藏
页码：701 / 735
页数：35
相关论文
共 225 条
[11]  
BASSINGTHWAIGHT.JB, 1984, HDB PHYSL 2, P549
[12]   A HISTORY OF THE STUDY OF THE CEREBRAL-CIRCULATION AND THE MEASUREMENT OF CEREBRAL BLOOD-FLOW [J].
BELL, BA .
NEUROSURGERY, 1984, 14 (02) :238-246
[13]   FUNCTIONAL MAPPING OF THE HUMAN VISUAL-CORTEX BY MAGNETIC-RESONANCE-IMAGING [J].
BELLIVEAU, JW ;
KENNEDY, DN ;
MCKINSTRY, RC ;
BUCHBINDER, BR ;
WEISSKOFF, RM ;
COHEN, MS ;
VEVEA, JM ;
BRADY, TJ ;
ROSEN, BR .
SCIENCE, 1991, 254 (5032) :716-719
[14]   FUNCTIONAL IMAGING OF THE BRAIN USING COMPUTED-TOMOGRAPHY [J].
BERNINGER, WH ;
AXEL, L ;
NORMAN, D ;
NAPEL, S ;
REDINGTON, RW .
RADIOLOGY, 1981, 138 (03) :711-716
[15]   Can cerebrovascular reactivity be assessed by dynamic susceptibility contrast-enhanced MRI? [J].
Berthezene, Y ;
Nighoghossian, N ;
Meyer, R ;
Damien, J ;
Cinotti, L ;
Adeleine, P ;
Trouillas, P ;
Froment, JC .
NEURORADIOLOGY, 1998, 40 (01) :1-5
[16]   Functional MRI of somatosensory activation in rat: Effect of hypercapnic up-regulation on perfusion- and BOLD-imaging [J].
Bock, C ;
Schmitz, B ;
Kerskens, CM ;
Gyngell, ML ;
Hossmann, KA ;
Hoehn-Berlage, M .
MAGNETIC RESONANCE IN MEDICINE, 1998, 39 (03) :457-461
[17]   Signal-to-noise analysis of cerebral blood volume maps from dynamic NMR imaging studies [J].
Boxerman, JL ;
Rosen, BR ;
Weisskoff, RM .
JMRI-JOURNAL OF MAGNETIC RESONANCE IMAGING, 1997, 7 (03) :528-537
[18]   MR CONTRAST DUE TO INTRAVASCULAR MAGNETIC-SUSCEPTIBILITY PERTURBATIONS [J].
BOXERMAN, JL ;
HAMBERG, LM ;
ROSEN, BR ;
WEISSKOFF, RM .
MAGNETIC RESONANCE IN MEDICINE, 1995, 34 (04) :555-566
[19]   Reperfusion after thrombolytic therapy of embolic stroke in the rat:: Magnetic resonance and biochemical imaging [J].
Busch, E ;
Krüger, K ;
Allegrini, PR ;
Kerskens, CM ;
Gyngell, ML ;
Hoehn-Berlage, M ;
Hossmann, KA .
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 1998, 18 (04) :407-418
[20]   A general kinetic model for quantitative perfusion imaging with arterial spin labeling [J].
Buxton, RB ;
Frank, LR ;
Wong, EC ;
Siewert, B ;
Warach, S ;
Edelman, RR .
MAGNETIC RESONANCE IN MEDICINE, 1998, 40 (03) :383-396
12345678910