Oxidative Stress-induced Aggregation of Keap1 Impairs Nrf2 Regulation

被引:2
|
作者
Vy Ngo [1 ]
Karunatilleke, Nadun [1 ]
Song, Zheng [1 ]
Brickenden, Anne [1 ]
Krstic, Milica [1 ]
Choy, Wing-Yiu [1 ]
Duennwald, Martin [1 ]
机构
[1] Western UnivY, London, ON, Canada
关键词
D O I
10.1016/j.freeradbiomed.2020.10.156
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
101
引用
收藏
页码:S58 / S58
页数:1
相关论文
共 50 条
  • [1] Oxidative Stress-Induced Misfolding and Inclusion Formation of Nrf2 and Keap1
    Ngo, Vy
    Karunatilleke, Nadun C.
    Brickenden, Anne
    Choy, Wing-Yiu
    Duennwald, Martin L.
    ANTIOXIDANTS, 2022, 11 (02)
  • [2] Protective effects of sesamol on systemic oxidative stress-induced cognitive impairments via regulation of Nrf2/Keap1 pathway
    Ren, Bo
    Yuan, Tian
    Diao, Zhijun
    Zhang, Chenxi
    Liu, Zhigang
    Liu, Xuebo
    FOOD & FUNCTION, 2018, 9 (11) : 5912 - 5924
  • [3] Cytoprotection of Baicalein Against Oxidative Stress-induced Cardiomyocytes Injury Through the Nrf2/Keap1 Pathway
    Cui, Guozhen
    Luk, Sharon Chui Wah
    Li, Ronald Adolphus
    Chan, Ken Kwok Keung
    Lei, Si Wan
    Wang, Liang
    Shen, Huifang
    Leung, George Pak Heng
    Lee, Simon Ming Yuen
    JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 2015, 65 (01) : 39 - 46
  • [4] Nrf2:INrf2 (Keap1) signaling in oxidative stress
    Kaspar, James W.
    Niture, Suryakant K.
    Jaiswal, Anil K.
    FREE RADICAL BIOLOGY AND MEDICINE, 2009, 47 (09) : 1304 - 1309
  • [5] Tea Polyphenol Attenuates Oxidative Stress-Induced Degeneration of Intervertebral Discs by Regulating the Keap1/Nrf2/ARE Pathway
    Song, Dawei
    Ge, Jun
    Wang, Yingjie
    Yan, Qi
    Wu, Cenhao
    Yu, Hao
    Yang, Ming
    Yang, Huilin
    Zou, Jun
    OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2021, 2021
  • [6] Epigenetic Regulation of NRF2/KEAP1 by Phytochemicals
    Bhattacharjee, Shamee
    Dashwood, Roderick H.
    ANTIOXIDANTS, 2020, 9 (09) : 1 - 22
  • [7] Protective mechanism against oxidative stress by Keap1/Nrf2 pathway
    Itoh, K
    SEIKAGAKU, 2006, 78 (02): : 79 - 92
  • [8] Protective Effects of Sal B on Oxidative Stress-Induced Aging by Regulating the Keap1/Nrf2 Signaling Pathway in Zebrafish
    Li, Erzhuo
    Wang, Yunhao
    Li, Qiao
    Li, Li
    Wei, Lijun
    MOLECULES, 2021, 26 (17):
  • [9] Engeletin Attenuates Aβ1–42-Induced Oxidative Stress and Neuroinflammation by Keap1/Nrf2 Pathway
    Zhixiong Huang
    Hu Ji
    Junfeng Shi
    Xinchen Zhu
    Zhongwen Zhi
    Inflammation, 2020, 43 : 1759 - 1771
  • [10] Engeletin Attenuates Aβ1-42-Induced Oxidative Stress and Neuroinflammation by Keap1/Nrf2 Pathway
    Huang, Zhixiong
    Ji, Hu
    Shi, Junfeng
    Zhu, Xinchen
    Zhi, Zhongwen
    INFLAMMATION, 2020, 43 (05) : 1759 - 1771