Angiogenesis in endometriosis and angiogenic factors

被引:29
作者
Fujimoto, J [1 ]
Sakaguchi, H [1 ]
Hirose, R [1 ]
Wen, HW [1 ]
Tamaya, T [1 ]
机构
[1] Gifu Univ, Sch Med, Dept Obstet & Gynecol, Gifu 5008705, Japan
关键词
angiogenesis; basic FGF; VEGF; PD-ECGF; ovarian endometriosis; gynecological cancers;
D O I
10.1159/000052864
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Among angiogenic factors, VEGF secreted from activated macrophages under the influence of ovarian steroids, IL-8 expressed in endometrial stromal cells, and basic FGF expressed in endometriotic tissue and PD-ECGF expressed in lining epithelial cells independently of the sex steroidal milieu might contribute to the characteristic advancement of angiogenic lesions in endometriosis in individual manners. Copyright (C) 1999 S. Karger AG, Basel.
引用
收藏
页码:14 / 18
页数:5
相关论文
共 41 条
[1]   Interleukin-8 induces proliferation of endometrial stromal cells: a potential autocrine growth factor [J].
Arici, A ;
Seli, E ;
Zeyneloglu, HB ;
Senturk, LM ;
Oral, E ;
Olive, DL .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1998, 83 (04) :1201-1205
[2]   Interleukin-8 concentration in peritoneal fluid of patients with endometriosis and modulation of interleukin-8 expression in human mesothelial cells [J].
Arici, Aydin ;
Tazuke, Salli, I ;
Attar, Erkut ;
Kliman, Harvey J. ;
Olive, David L. .
MOLECULAR HUMAN REPRODUCTION, 1996, 2 (01) :40-45
[3]   Basic fibroblast growth factor messenger ribonucleic acid levels in eutopic and ectopic human endometrial stromal cells as assessed by competitive polymerase chain reaction amplification [J].
DiBlasio, AM ;
Centinaio, G ;
Carniti, C ;
Somigliana, E ;
Vigano, P ;
Vignali, M .
MOLECULAR AND CELLULAR ENDOCRINOLOGY, 1995, 115 (02) :169-175
[4]   IMMUNOHISTOCHEMICAL LOCALIZATION OF ACIDIC AND BASIC FIBROBLAST GROWTH-FACTORS IN NORMAL HUMAN ENDOMETRIUM AND ENDOMETRIOSIS AND THE DETECTION OF THEIR MESSENGER-RNA BY POLYMERASE CHAIN-REACTION [J].
FERRIANI, RA ;
CHARNOCKJONES, DS ;
PRENTICE, A ;
THOMAS, EJ ;
SMITH, SK .
HUMAN REPRODUCTION, 1993, 8 (01) :11-16
[5]   ANGIOGENESIS INVITRO [J].
FOLKMAN, J ;
HAUDENSCHILD, C .
NATURE, 1980, 288 (5791) :551-556
[6]   TUMOR ANGIOGENESIS [J].
FOLKMAN, J .
ADVANCES IN CANCER RESEARCH, 1985, 43 :175-203
[7]  
FUJIMOTO J, 1989, INVAS METAST, V9, P209
[8]  
Fujimoto J, 1997, EUR J GYNAECOL ONCOL, V18, P349
[9]   Expression of platelet-derived endothelial cell growth factor (PD-ECGF) related to angiogenesis in ovarian endometriosis [J].
Fujimoto, J ;
Sakaguchi, H ;
Hirose, R ;
Tamaya, T .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1999, 84 (01) :359-362
[10]   Expression of platelet-derived endothelial cell growth factor (PD-ECGF) and its mRNA in ovarian cancers [J].
Fujimoto, J ;
Ichigo, S ;
Sakaguchi, H ;
Hirose, R ;
Tamaya, T .
CANCER LETTERS, 1998, 126 (01) :83-88