Appendectomy increased the risk of ischemic heart disease

被引:15
|
作者
Chen, Chao-Hung [1 ,2 ,3 ]
Tsai, Ming-Chieh [4 ]
Lin, Herng-Ching [5 ]
Lee, Hsin-Chien [6 ]
Lee, Cha-Ze [7 ]
Chung, Shiu-Dong [8 ,9 ]
机构
[1] Mackay Jr Coll Med Nursing & Management, Dept Cosmet Applicat & Management, Taipei, Taiwan
[2] MacKay Mem Hosp, Dept Thorac Surg, Taipei, Taiwan
[3] Natl Yang Ming Univ, Dept & Inst Physiol, Taipei 112, Taiwan
[4] Cathay Gen Hosp, Dept Internal Med, Div Gastroenterol, Taipei, Taiwan
[5] Taipei Med Univ Hosp, Sleep Res Ctr, Taipei, Taiwan
[6] Taipei Med Univ, Coll Med, Dept Psychiat, Taipei, Taiwan
[7] Natl Taiwan Univ Hosp, Dept Internal Med, Taipei 100, Taiwan
[8] Far Eastern Mem Hosp, Dept Surg, New Taipei City 220, Taiwan
[9] Fu Jen Catholic Univ, Sch Med, New Taipei City, Taiwan
关键词
Appendix; Appendectomy; Ischemic heart disease; ULCERATIVE-COLITIS; APPENDICITIS; ATHEROSCLEROSIS; INFLAMMATION; SURGERY; SAFETY;
D O I
10.1016/j.jss.2015.06.049
中图分类号
R61 [外科手术学];
学科分类号
摘要
Background: Although the appendix may not be considered vital, recent studies have noted adverse health consequences after appendectomy. This study aimed to use a population-based data set to explore whether appendectomy increases the risk for subsequent ischemic heart disease (IHD) in a 3-y follow-up period. Materials and methods: This study used data from the Longitudinal Health Insurance Database 2000 in Taiwan. The study cohort included 5413 patients who underwent appendectomies. The comparison cohort was selected by randomly recruiting 16,239 enrollees matched with the study group in terms of sex, age, hypertension, hyperlipidemia, and diabetes. Each individual was tracked for 3 y to identify whether he and/or she developed IHD during the follow-up period. Cox proportional hazard regressions were performed for analysis. Results: During a 3-y follow-up, 196 (3.62%) and 375 (2.31%) IHD incidents developed in the study and the comparison cohorts, respectively. For adults aged >= 18 y, experiencing an appendectomy was independently associated with a 1.54-fold increased risk of IHD during the 3 y of follow-up (95% CI = 1.29-1.84). The association persisted in further analyses stratified by age. Conclusions: There is an increased risk of subsequent IHD within 3 y after appendectomy, and this underscores the need for more serious clinical decision-making in removing the appendix. Regular monitoring for IHDs is also recommended for patients who have undergone an appendectomy. (C) 2015 Elsevier Inc. All rights reserved.
引用
收藏
页码:435 / 440
页数:6
相关论文
共 50 条
  • [21] Women and Ischemic Heart Disease Paradox and Pathophysiology
    Merz, C. Noel Bairey
    JACC-CARDIOVASCULAR IMAGING, 2011, 4 (01) : 74 - 77
  • [22] The Risk of Alzheimer's Disease After Acute Appendicitis With or Without Appendectomy
    Liang, Chih-Sung
    Bai, Ya-Mei
    Hsu, Ju-Wei
    Huang, Kai-Lin
    Chu, Che-Sheng
    Yeh, Ta-Chuan
    Tsai, Shih-Jen
    Chen, Tzeng-Ji
    Chen, Mu-Hong
    JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION, 2022, 23 (04) : 601 - +
  • [23] Ischemic Heart Disease in Patients with Inflammatory Bowel Disease: Risk Factors, Mechanisms and Prevention
    Jucan, Alina Ecaterina
    Gavrilescu, Otilia
    Dranga, Mihaela
    Popa, Iolanda Valentina
    Mihai, Bogdan Mircea
    Prelipcean, Cristina Cijevschi
    Mihai, Catalina
    LIFE-BASEL, 2022, 12 (08):
  • [24] Increased ventricular sialylation in patients with heart failure secondary to ischemic heart disease
    Crook, JR
    Goldman, JH
    Dalziel, M
    Madden, B
    McKenna, WJ
    CLINICAL CARDIOLOGY, 1997, 20 (05) : 455 - 458
  • [25] Evaluating the Factors Associated With Increased Risk of Self-Reported Ischemic Heart Disease in Patients With Arthritis
    Sharma, Akash
    Ananthan, Velmurugan Anbu
    Yousaf, Hamza
    AMERICAN JOURNAL OF LIFESTYLE MEDICINE, 2024,
  • [26] Prior appendectomy and cerebral infarction as potential risk factors for recurrent ischemic colitis: A retrospective observational study
    Takatsu, Tomohiro
    Misawa, Noboru
    Yoshihara, Tsutomu
    Ashikari, Keiichi
    Kessoku, Takaomi
    Ohkubo, Hidenori
    Hosono, Kunihiro
    Yoneda, Masato
    Saito, Satoru
    Nakajima, Atsushi
    Higurashi, Takuma
    JGH OPEN, 2023, 7 (08): : 559 - 566
  • [27] The Impact of Hepatitis C Infection on Ischemic Heart Disease Via Ischemic Electrocardiogram
    Lin, Ming-Shyan
    Guo, Su-Er
    Chen, Mei-Yen
    Huang, Tung-Jung
    Huang, Jui-Chu
    Hu, Jing-Hong
    Lin, Yu-Sheng
    AMERICAN JOURNAL OF THE MEDICAL SCIENCES, 2014, 347 (06) : 478 - 484
  • [28] Increased risk of ischemic heart disease among subjects with cataracts A population-based cohort study
    Hu, Wei-Syun
    Lin, Cheng-Li
    Chang, Shih-Sheng
    Chen, Ming-Fong
    Chang, Kuan-Cheng
    MEDICINE, 2016, 95 (28)
  • [29] Appendectomy and Risk of Advanced Colorectal Neoplasia in Inflammatory Bowel Disease: A Nationwide Population-based Cohort Study
    Mark-Christensen, Anders
    Kristiansen, Eskild Bendix
    Myrelid, Paer
    Laurberg, Soren
    Erichsen, Rune
    INFLAMMATORY BOWEL DISEASES, 2024, 30 (06) : 877 - 883
  • [30] Inflammation, lipids and cardiovascular risk: The quest for improving risk stratification and prognosis in ischemic heart disease
    Romiti, Giulio Francesco
    Buoninfante, Giovanni
    Basili, Stefania
    EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, 2025, 55 (04)