Second primary cancer in survivors following concurrent chemoradiation for locally advanced non-small-cell lung cancer

被引:23
作者
Takigawa, N. [1 ]
Kiura, K.
Segawa, Y.
Watanabe, Y.
Kamei, H.
Moritaka, T.
Shibayama, T.
Ueoka, H.
Gemba, K.
Yonei, T.
Tabata, M.
Shinkai, T.
Hiraki, S.
Takemoto, M.
Kanazawa, S.
Matsuo, K.
Tanimoto, M.
机构
[1] Okayama Univ, Dept Hematol Oncol & Resp Med, Grad Sch Med Dent & Pharmaceut Sci, Okayama 7008558, Japan
[2] Okayama Univ Hosp, Okayama 7008558, Japan
[3] Natl Hosp Org, Shikoku Canc Ctr, Dept Med & Thorac Oncol, Matsuyama, Ehime 7910288, Japan
[4] Okayama Red Cross Hosp, Dept Internal Med, Okayama 7008607, Japan
[5] Sumitomo Besshi Gen Hosp, Dept Internal Med, Niihama 7928543, Japan
[6] Ehime Prefectural Cent Hosp, Dept Pulm Med, Matsuyama, Ehime 7900024, Japan
[7] Natl Hosp Org, Minami Okayama Med Ctr, Dept Pulm Med, Tsukuba 7010304, Japan
[8] Sanyo Hosp, Natl Hosp Org, Dept Med, Ube, Yamaguchi 7550241, Japan
[9] Okayama Rosai Hosp, Dept Pulm Med, Okayama 7028055, Japan
[10] Okayama Med Ctr, Dept Pulm Med, Okayama 7011192, Japan
[11] Okayama Univ, Dept Radiol, Grad Sch Med Dent & Pharmaceut Sci, Okayama 7008558, Japan
[12] Aichi Canc Ctr, Inst Res, Dept Epidemiol & Prevent, Nagoya, Aichi 4948681, Japan
关键词
non-small-cell lung cancer; chemotherapy; radiotherapy; second primary cancer;
D O I
10.1038/sj.bjc.6603422
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Long-term cancer survivors risk development of second primary cancers (SPC). Vigilant follow-up may be required. We report outcomes of 92 patients who underwent chemoradiation for unresectable stage III non-small-cell lung cancer, with a median followup of 8.9 years. The incidence of SPC was 2.4 per 100 patient- years (95% confidence interval: 1.0 - 4.9).
引用
收藏
页码:1142 / 1144
页数:3
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