Second primary cancer in survivors following concurrent chemoradiation for locally advanced non-small-cell lung cancer

被引:22
作者
Takigawa, N. [1 ]
Kiura, K.
Segawa, Y.
Watanabe, Y.
Kamei, H.
Moritaka, T.
Shibayama, T.
Ueoka, H.
Gemba, K.
Yonei, T.
Tabata, M.
Shinkai, T.
Hiraki, S.
Takemoto, M.
Kanazawa, S.
Matsuo, K.
Tanimoto, M.
机构
[1] Okayama Univ, Dept Hematol Oncol & Resp Med, Grad Sch Med Dent & Pharmaceut Sci, Okayama 7008558, Japan
[2] Okayama Univ Hosp, Okayama 7008558, Japan
[3] Natl Hosp Org, Shikoku Canc Ctr, Dept Med & Thorac Oncol, Matsuyama, Ehime 7910288, Japan
[4] Okayama Red Cross Hosp, Dept Internal Med, Okayama 7008607, Japan
[5] Sumitomo Besshi Gen Hosp, Dept Internal Med, Niihama 7928543, Japan
[6] Ehime Prefectural Cent Hosp, Dept Pulm Med, Matsuyama, Ehime 7900024, Japan
[7] Natl Hosp Org, Minami Okayama Med Ctr, Dept Pulm Med, Tsukuba 7010304, Japan
[8] Sanyo Hosp, Natl Hosp Org, Dept Med, Ube, Yamaguchi 7550241, Japan
[9] Okayama Rosai Hosp, Dept Pulm Med, Okayama 7028055, Japan
[10] Okayama Med Ctr, Dept Pulm Med, Okayama 7011192, Japan
[11] Okayama Univ, Dept Radiol, Grad Sch Med Dent & Pharmaceut Sci, Okayama 7008558, Japan
[12] Aichi Canc Ctr, Inst Res, Dept Epidemiol & Prevent, Nagoya, Aichi 4948681, Japan
关键词
non-small-cell lung cancer; chemotherapy; radiotherapy; second primary cancer;
D O I
10.1038/sj.bjc.6603422
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Long-term cancer survivors risk development of second primary cancers (SPC). Vigilant follow-up may be required. We report outcomes of 92 patients who underwent chemoradiation for unresectable stage III non-small-cell lung cancer, with a median followup of 8.9 years. The incidence of SPC was 2.4 per 100 patient- years (95% confidence interval: 1.0 - 4.9).
引用
收藏
页码:1142 / 1144
页数:3
相关论文
共 13 条
  • [1] Mechanisms of therapy-related carcinogenesis
    Allan, JM
    Lois, BT
    [J]. NATURE REVIEWS CANCER, 2005, 5 (12) : 943 - 955
  • [2] Concomitant radio-chemotherapy based on platin compounds in patients with locally advanced non-small cell lung cancer (NSCLC):: A meta-analysis of individual data from 1764 patients
    Aupérin, A
    Le Péchoux, C
    Pignon, JP
    Koning, C
    Jeremic, B
    Clamon, G
    Einhorn, L
    Ball, D
    Trovo, MG
    Groen, HJM
    Bonner, JA
    Le Chevalier, T
    Arriagada, R
    [J]. ANNALS OF ONCOLOGY, 2006, 17 (03) : 473 - 483
  • [3] Does the incidence and outcome of brain metastases in locally advanced non-small cell lung cancer justify prophylactic cranial irradiation or early detection?
    Carolan, H
    Sun, AY
    Bezjak, A
    Yi, QL
    Payne, D
    Kane, G
    Waldron, J
    Leighl, N
    Feld, R
    Burkes, R
    Keshavjee, S
    Shepherd, F
    [J]. LUNG CANCER, 2005, 49 (01) : 109 - 115
  • [4] Second primary tumors involving non-small cell lung cancer - Prevalence and its influence on survival
    Duchateau, CSJ
    Stokkel, MPM
    [J]. CHEST, 2005, 127 (04) : 1152 - 1158
  • [5] Time from treatment to subsequent diagnosis of brain, metastases in stage III non-small-cell lung cancer: A retrospective review by the southwest oncology group
    Gaspar, LE
    Chansky, K
    Albain, KS
    Vallieres, E
    Rusch, V
    Crowley, JJ
    Livingston, RB
    Gandara, DR
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (13) : 2955 - 2961
  • [6] RANDOMIZED TRIAL OF LOBECTOMY VERSUS LIMITED RESECTION FOR T1 N0 NON-SMALL-CELL LUNG-CANCER
    HOLMES, CE
    RUCKDESCHEL, JC
    JOHNSTON, M
    THOMAS, PA
    DESLAURIERS, J
    GROVER, FL
    HILL, LD
    FELD, R
    GINSBERG, RJ
    MOUNTAIN, CF
    DZUIBAN, S
    KIELY, M
    MCKNEALLY, MF
    MOORES, DWO
    RAMNES, C
    WAGNER, H
    BUNN, P
    CHU, H
    DIENHART, D
    HAZUKA, M
    KINZIE, J
    SORENSEN, J
    VANCE, V
    BRAUN, T
    HOPEMAN, A
    KANE, M
    RUSS, P
    WHITMAN, GJR
    FALL, SM
    HANSEN, DP
    HENDERSON, RH
    MONCRIEF, CL
    PAULING, F
    SIMS, J
    TELL, D
    WISELYCARR, S
    ABERNATHY, CM
    CLARK, DA
    MCCROSKEY, B
    MOORE, G
    MOORE, F
    MYERS, A
    WHITE, M
    BROOKS, RJ
    BULL, M
    JOHNSON, FB
    NEIMYR, M
    PAQUETTE, FR
    SACCOMANNO, G
    LAD, T
    [J]. ANNALS OF THORACIC SURGERY, 1995, 60 (03) : 615 - 622
  • [7] Second cancers occurring in patients with early stage non-small-cell lung cancer treated with chest radiation therapy alone
    Jeremic, B
    Shibamoto, Y
    Acimovic, L
    Nikolic, N
    Dagovic, A
    Aleksandrovic, J
    Radosavljevic-Asic, G
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2001, 19 (04) : 1056 - 1063
  • [8] Second primary cancers in patients with stage III non-small cell lung cancer successfully treated with chemo-radiotherapy
    Kawaguchi, T
    Matsumura, A
    Iuchi, K
    Ishikawa, S
    Maeda, H
    Fukai, S
    Komatsu, H
    Kawahara, M
    [J]. JAPANESE JOURNAL OF CLINICAL ONCOLOGY, 2006, 36 (01) : 7 - 11
  • [9] Phase I/II study of docetaxel and cisplatin with concurrent thoracic radiation therapy for locally advanced non-small-cell lung cancer
    Kiura, K
    Ueoka, H
    Segawa, Y
    Tabata, M
    Kamei, H
    Takigawa, N
    Hiraki, S
    Watanabe, Y
    Bessho, A
    Eguchi, K
    Okimoto, N
    Harita, S
    Takemoto, M
    Hiraki, Y
    Harada, M
    Tanimoto, M
    [J]. BRITISH JOURNAL OF CANCER, 2003, 89 (05) : 795 - 802
  • [10] MARTINI N, 1975, J THORAC CARDIOV SUR, V70, P606