The role of N-terminal pro-B-type natriuretic peptide in prognostic evaluation of heart failure

被引：18

作者：

Lam, Carolyn S. P. ^{[1
,2
,3
,4
]}

Li, Yi-Heng ^{[5
]}

Bayes-Genis, Antoni ^{[6
]}

Ariyachaipanich, Aekarach ^{[7
]}

Do Quang Huan ^{[8
]}

Sato, Naoki ^{[9
]}

Kahale, Pravin ^{[10
]}

Ta Manh Cuong ^{[11
]}

Dong, Yugang ^{[12
]}

Li, Xinli ^{[13
]}

Zhou, Yanli ^{[13
]}

机构：

[1] Natl Heart Ctr Singapore, Singapore, Singapore

[2] Duke Natl Univ Singapore, Singapore, Singapore

[3] Univ Med Ctr Groningen, Groningen, Netherlands

[4] George Inst Global Hlth, Newtown, NSW, Australia

[5] Natl Cheng Kung Univ, Natl Cheng Kung Univ Hosp, Coll Med, Tainan, Taiwan

[6] Germans Trias & Pujol Univ Hosp, CIBERCV, Barcelona, Spain

[7] Chulalongkorn Univ, Bangkok, Thailand

[8] Heart Inst Ho Chi Minh City, Ho Chi Minh City, Vietnam

[9] Nippon Med Sch Musashi Kosugi Hosp, Kawasaki, Kanagawa, Japan

[10] Kokilaben Dhirubhai Ambani Hosp, Mumbai, Maharashtra, India

[11] Bach Mai Hosp, Vietnam Heart Inst, Hanoi, Vietnam

[12] Sun Yat Sen Univ, Guangzhou, Guangdong, Peoples R China

[13] Jiangsu Prov Hosp, Nanjing, Jiangsu, Peoples R China

来源：

JOURNAL OF THE CHINESE MEDICAL ASSOCIATION | 2019年 / 82卷 / 06期

关键词：

Heart failure; Natriuretic peptide; Prognosis; REDUCED EJECTION FRACTION; DIAGNOSIS; MORTALITY; THERAPY; RISK; ASIA; HOSPITALIZATION; COMBINATION; PERFORMANCE; POPULATION;

D O I：

10.1097/JCMA.0000000000000102

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Heart failure (HF) is a growing challenge in the Asia Pacific region. N-terminal pro-B-type natriuretic peptide (NT-proBNP) is a well-established tool for diagnosis of HF; however, it is relatively underutilized in predicting adverse outcomes in HF. Multiple studies have demonstrated the prognostic role of NT-proBNP in HF. A single value of NT-proBNP >5000 pg/mL predicts a worse outcome in hospitalized patients with HF with reduced ejection fraction (HFrEF). In stable outpatients with HFrEF, NT-proBNP > 1000 pg/mL predicts a poorer prognosis. NT-proBNP provides the same prognostic information in patients with HF with preserved ejection fraction (HFpEF) as in those with HFrEF. An expert panel composed of cardiologists mainly from Asia Pacific region was convened to discuss the utility of NT-proBNP in HF prognostication. This article summarizes available scientific evidence and consensus recommendations from the meeting.

引用

页码：447 / 451

页数：5

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