Supervised Physical Training Improves Weight Loss After Roux-en-Y Gastric Bypass Surgery: A Randomized Controlled Trial

被引:48
作者
Mundbjerg, Lene Hymoller [1 ,2 ,3 ]
Stolberg, Charlotte Ron [1 ,2 ,3 ]
Cecere, Stefano [4 ]
Bladbjerg, Else-Marie [2 ,5 ]
Funch-Jensen, Peter [6 ]
Gram, Bibi [2 ]
Juhl, Claus Bogh [1 ,2 ]
机构
[1] Hosp Southwest Jutland, Dept Med Endocrinol, Esbjerg, Denmark
[2] Univ Southern Denmark, Dept Reg Hlth Res, Odense, Denmark
[3] Odense Univ Hosp, Odense Patient Data Explorat Network, Odense, Denmark
[4] Copenhagen Univ Hosp, Dept Diagnost Radiol, Herlev, Denmark
[5] Hosp Southwest Jutland, Dept Clin Biochem, Unit Thrombosis Res, Esbjerg, Denmark
[6] Aarhus Univ Hosp, Dept Clin Med, Aarhus, Denmark
关键词
BARIATRIC SURGERY; BODY-COMPOSITION; LONGITUDINAL ASSESSMENT; INSULIN SENSITIVITY; HEALTH-BENEFITS; EXERCISE; FITNESS; OBESITY; ADULTS; FACILITATORS;
D O I
10.1002/oby.22143
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
ObjectiveBariatric surgery results in significant weight loss and reduces cardiovascular morbidity. However, a large variation in postsurgery weight loss is seen. Physical activity promotes weight loss in nonsurgically treated subjects with obesity. The aim of this study was to investigate the effects of 6 months of supervised physical training following Roux-en-Y gastric bypass surgery (RYGB) on body weight and cardiovascular risk markers. MethodsSixty participants eligible for RYGB were included. Six months post surgery, the participants were randomly assigned to either twice-weekly supervised physical training sessions in a fitness center (INT) or a control group (CON) for 26 weeks. Before surgery and 6, 12, and 24 months after surgery, the participants underwent an examination program that included anthropometric measurements, blood pressure, heart rate, blood samples, and an abdominal computed tomography scan. ResultsRYGB significantly reduced body weight and improved cardiovascular risk markers (all P<0.01). The supervised physical training intervention resulted in a 4.2-kg (CI: -0.2 to -8.3 kg) lower body weight in INT compared with CON at the study end (P=0.042). The high-density lipoprotein concentration was significantly higher in INT than in CON at the termination of the intervention, but this was not maintained at the 24-months examination. ConclusionsPhysical training following RYGB improves weight loss and cardiovascular health.
引用
收藏
页码:828 / 837
页数:10
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