Staphylococcal Skin and Soft Tissue Infections

被引:60
作者
Hatlen, Timothy J. [1 ,2 ,3 ,4 ]
Miller, Loren G. [3 ,4 ,5 ]
机构
[1] Harbor UCLA Med Ctr, Div Infect Dis, Torrance, CA 90509 USA
[2] Harbor UCLA Med Ctr, Div HIV, Torrance, CA 90509 USA
[3] Harbor UCLA Med Ctr, Lundquist Inst Biomed Innovat, Torrance, CA 90509 USA
[4] Univ Calif Los Angeles, David Geffen Sch Med, Los Angeles, CA 90095 USA
[5] Harbor UCLA Med Ctr, 1000 West Carson St,Box 466, Torrance, CA 90509 USA
关键词
Cellulitis with abscess; Purulent cellulitis; Suppurative cellulitis; Staphylococcus aureus skin infection; Acute bacterial skin and skin structure infections; ACUTE BACTERIAL SKIN; ONCE-WEEKLY DALBAVANCIN; COMPLICATED SKIN; TRIMETHOPRIM-SULFAMETHOXAZOLE; AUREUS INFECTIONS; DOUBLE-BLIND; FUSIDIC ACID; NECROTIZING FASCIITIS; CLINICAL-OUTCOMES; RESISTANT;
D O I
10.1016/j.idc.2020.10.003
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Staphylococcus aureus is the most common bacteria causing purulent skin and soft tissue infections. Many disease-causing S aureus strains are methicillin resistant; thus, empiric therapy should be given to cover methicillin-resistant S aureus. Bacterial wound cultures are important for characterizing local susceptibility patterns. Definitive antibiotic therapy is warranted, although there are no compelling data demonstrating superiority of any one antibiotic over another. Antibiotic choice is predicated by the infection severity, local susceptibility patterns, and drug-related safety, tolerability, and cost. Response to therapy is expected within the first days; 5 to 7 days of therapy is typically adequate to achieve cure. © 2020 Elsevier Inc.
引用
收藏
页码:81 / 105
页数:25
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