Transforming growth factor-alpha, like epidermal growth factor, stimulates cell proliferation and inhibits prolactin secretion in the human decidual cells in vitro

被引：6
|
作者：
Taga, M
Saji, M
Suyama, K
Minaguchi, H
机构：
[1] Department of Obstetrics, Yokohama City University, School of Medicine, Yokohama
[2] Department of Oostetrics, Yokonama City University, School of Medicine, Kanazawa-ku, Yokohama 236
来源：
JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION | 1996年 / 19卷 / 10期
关键词：
TGF-alpha; decidua; PRL; cell proliferation; MEDIATOR;
D O I：
10.1007/BF03349035
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
In order to clarify the biological action of transforming growth factor alpha (TGF-alpha) in the human decidua, we investigated the effects of TGF-alpha on cell proliferation and prolactin (PRL) secretion in cultured decidual cells in vitro. TGF-alpha had a stimulatory effect on DNA synthesis in decidual cells and an inhibitory effect on PRL secretion from these cells. These results suggest that TGF-alpha, like epidermal growth factor (EGF), may be one of the substances which regulate decidual function.
引用
收藏
页码：659 / 662
页数：4
相关论文
共 50 条
  • [41] TRANSFORMING GROWTH FACTOR-ALPHA (TGF-ALPHA) AND INSULIN GENE-EXPRESSION IN HUMAN FETAL PANCREAS
    MIETTINEN, PJ
    HEIKINHEIMO, K
    DEVELOPMENT, 1992, 114 (04): : 833 - 840
  • [42] Study of transforming growth factor alpha for the maintenance of human embryonic stem cells
    Chen, Andy C. H.
    Lee, Y. L.
    Hou, Denise Y. C.
    Fong, S. W.
    Peng, Qian
    Pang, Ronald T. K.
    Chiu, Phillip C. N.
    Ho, P. C.
    Lee, Kai-Fai
    Yeung, William S. B.
    CELL AND TISSUE RESEARCH, 2012, 350 (02) : 289 - 303
  • [43] Transforming growth factor-alpha, epidermal growth factor receptor, and PCNA immunoexpression in uterine leiomyosarcomas and leiomyomas in B6C3F1 mice
    Moore, AB
    He, H
    Yoshida, A
    Rico, PJ
    Haseman, JK
    Dixon, D
    EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY, 2000, 52 (03) : 195 - 200
  • [44] Effect of epidermal growth factor and insulin-like growth factor I on porcine preantral follicular growth, antrum formation, and stimulation of granulosal cell proliferation and suppression of apoptosis in vitro
    Mao, J
    Smith, MF
    Rucker, EB
    Wu, GM
    McCauley, TC
    Cantley, TC
    Prather, RS
    Didion, BA
    Day, BN
    JOURNAL OF ANIMAL SCIENCE, 2004, 82 (07) : 1967 - 1975
  • [45] EXPRESSION OF TRANSFORMING GROWTH FACTOR-ALPHA IN REGENERATING LIVER AND DURING HEPATIC DIFFERENTIATION
    EVARTS, RP
    NAKATSUKASA, H
    MARSDEN, ER
    HU, ZY
    THORGEIRSSON, SS
    MOLECULAR CARCINOGENESIS, 1992, 5 (01) : 25 - 31
  • [46] Paracrine action of transforming growth factor-alpha in rectal crypt epithelium of humans
    Cameron, IL
    Hardman, WE
    CELL BIOLOGY INTERNATIONAL, 2002, 26 (12) : 1029 - 1034
  • [47] Epidermal Growth Factor Receptor Cell Proliferation Signaling Pathways
    Wee, Ping
    Wang, Zhixiang
    CANCERS, 2017, 9 (05)
  • [48] Low-molecular-weight heparins induce decidual heparin-binding epidermal growth factor-like growth factor expression and promote survival of decidual cells undergoing apoptosis
    Di Simone, Nicoletta
    Di Nicuolo, Fiorella
    Castellani, Roberta
    Veglia, Manuela
    Tersigni, Chiara
    Silano, Marco
    Tritarelli, Alessandra
    Scambia, Giovanni
    Marana, Riccardo
    FERTILITY AND STERILITY, 2012, 97 (01) : 169 - U320
  • [49] EFFECT OF EPIDERMAL GROWTH-FACTOR, HEPATOCYTE GROWTH-FACTOR, AND KERATINOCYTE GROWTH-FACTOR, ON PROLIFERATION, MOTILITY AND DIFFERENTIATION OF HUMAN CORNEAL EPITHELIAL-CELLS
    WILSON, SE
    HE, YG
    WENG, JA
    ZIESKE, JD
    JESTER, JV
    SCHULTZ, GS
    EXPERIMENTAL EYE RESEARCH, 1994, 59 (06) : 665 - 678
  • [50] TRANSFORMING GROWTH FACTOR-ALPHA, FACTOR-BETA-1 AND FACTOR-BETA-2 IN BREAST CYST FLUID
    LAI, LC
    SIRAJ, AK
    ERBAS, H
    LENNARD, TWJ
    ANTICANCER RESEARCH, 1994, 14 (6B) : 2805 - 2809
12345