Transforming growth factor-alpha, like epidermal growth factor, stimulates cell proliferation and inhibits prolactin secretion in the human decidual cells in vitro

被引：6
|
作者：
Taga, M
Saji, M
Suyama, K
Minaguchi, H
机构：
[1] Department of Obstetrics, Yokohama City University, School of Medicine, Yokohama
[2] Department of Oostetrics, Yokonama City University, School of Medicine, Kanazawa-ku, Yokohama 236
来源：
JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION | 1996年 / 19卷 / 10期
关键词：
TGF-alpha; decidua; PRL; cell proliferation; MEDIATOR;
D O I：
10.1007/BF03349035
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
In order to clarify the biological action of transforming growth factor alpha (TGF-alpha) in the human decidua, we investigated the effects of TGF-alpha on cell proliferation and prolactin (PRL) secretion in cultured decidual cells in vitro. TGF-alpha had a stimulatory effect on DNA synthesis in decidual cells and an inhibitory effect on PRL secretion from these cells. These results suggest that TGF-alpha, like epidermal growth factor (EGF), may be one of the substances which regulate decidual function.
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页码：659 / 662
页数：4
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