Display of Peptides on the Surface of Tobacco Mosaic Virus Particles

被引：0

作者：

Smith, M. L. ^{[2
]}

Fitzmaurice, W. P. ^{[3
]}

Turpen, T. H. ^{[4
]}

Palmer, K. E. ^{[1
]}

机构：

[1] Univ Louisville, Owensboro Canc Res Program, Owensboro, KY 42303 USA

[2] Large Scale Biol Corp, Vacaville, CA 95688 USA

[3] Novici Biotech, Vacaville, CA 95688 USA

[4] Technol Innovat Grp Inc, Austin, TX 78750 USA

来源：

PLANT-PRODUCED MICROBIAL VACCINES | 2009年 / 332卷

关键词：

tobacco mosaic virus; vaccine; plant; virus-like particle; papillomavirus; MALARIA VACCINE; EPITOPES; PROTEIN; IMMUNOGENICITY; INACTIVATION; PURIFICATION; PROTECTION; EXPRESSION; RESPONSES; ANTIGEN;

D O I：

暂无

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In this review, we focus on the potential that tobacco mosaic virus (TMV) has as a carrier for immunogenic epitopes, and the factors that must be considered in order to bring products based on this platform to the market. Large Scale Biology Corporation developed facile and scaleable methods for manufacture of candidate peptide display vaccines based on TMV. We describe how rational design of., peptide vaccines can improve the manufacturability of particular TMV products. We also discuss downstream processing and purification of the vaccine products, with particular attention to the metrics that a product must attain in order to meet criteria for regulatory approval as injectable biologics.

引用

页码：13 / 31

页数：19

共 50 条

[21] Making a Virus Visible: Francis O. Holmes and a Biological Assay for Tobacco mosaic virus
Scholthof, Karen-Beth G.
JOURNAL OF THE HISTORY OF BIOLOGY, 2014, 47 (01) : 107 - 145
[22] Study on Antiviral Activity of Two Recombinant Antimicrobial Peptides Against Tobacco Mosaic Virus
Sabokkhiz, Mohammad Ali
Tanhaeian, Abbas
Mamarabadi, Mojtaba
PROBIOTICS AND ANTIMICROBIAL PROTEINS, 2019, 11 (04) : 1370 - 1378
[23] Deposition of platinum clusters on surface-modified tobacco mosaic virus
Lee, SY
Choi, JW
Royston, E
Janes, DB
Culver, JN
Harris, MT
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, 2006, 6 (04) : 974 - 981
[24] Dual display hemagglutinin 1 and 5 on the surface of enveloped virus-like particles in silkworm expression system
Goffar, Muzajjad Gozal
Deo, Vipin Kumar
Kato, Tatsuya
Park, Enoch Y.
PROTEIN EXPRESSION AND PURIFICATION, 2022, 197
[25] Elucidation of the viral disassembly switch of tobacco mosaic virus
Weis, Felix
Beckers, Maximilian
von Der Hocht, Iris
Sachse, Carsten
EMBO REPORTS, 2019, 20 (11)
[26] Antiviral activity of Eupatorium adenophorum leaf extract against tobacco mosaic virus
Jin, Yi
Hou, Lingyu
Zhang, Miaozhi
Tian, Zhaofeng
Cao, Aocheng
Xie, Xiangming
CROP PROTECTION, 2014, 60 : 28 - 33
[27] The coat protein of tobacco mosaic virus as an anti-tobacco mosaic virus: a molecular dynamics simulation
Sheibani, Narjes
Arab, Seyed Shahriar
Kamalvand, Mohammad
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2023, 41 (23) : 13792 - 13797
[28] Stable Display of Artificially Long Foreign Antigens on Chimeric Bamboo mosaic virus Particles
Chen, Tsung-Hsien
Hu, Chung-Chi
Lee, Chin-Wei
Feng, Yu-Min
Lin, Na-Sheng
Hsu, Yau-Heiu
VIRUSES-BASEL, 2021, 13 (04):
[29] Mechanism of action of isobavachalcone in inducing resistance to tobacco mosaic virus disease in tobacco
Guan, Lijie
Shang, Jinyu
Li, Xuelong
Liu, Chengjin
Liu, Lingyun
Lei, Xiaoyan
PHYSIOLOGICAL AND MOLECULAR PLANT PATHOLOGY, 2024, 134
[30] Antiviral agent fTDP stimulates the SA signaling pathway and enhances tobacco defense against tobacco mosaic virus
Han, Xiaoxiao
Zhang, Yahong
Zhang, Zhiyun
Xiao, Hua
Wu, Liping
Wu, Lan
PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 2022, 180

← 1 2 3 4 5 →