Display of Peptides on the Surface of Tobacco Mosaic Virus Particles

被引：0

作者：

Smith, M. L. ^{[2
]}

Fitzmaurice, W. P. ^{[3
]}

Turpen, T. H. ^{[4
]}

Palmer, K. E. ^{[1
]}

机构：

[1] Univ Louisville, Owensboro Canc Res Program, Owensboro, KY 42303 USA

[2] Large Scale Biol Corp, Vacaville, CA 95688 USA

[3] Novici Biotech, Vacaville, CA 95688 USA

[4] Technol Innovat Grp Inc, Austin, TX 78750 USA

来源：

PLANT-PRODUCED MICROBIAL VACCINES | 2009年 / 332卷

关键词：

tobacco mosaic virus; vaccine; plant; virus-like particle; papillomavirus; MALARIA VACCINE; EPITOPES; PROTEIN; IMMUNOGENICITY; INACTIVATION; PURIFICATION; PROTECTION; EXPRESSION; RESPONSES; ANTIGEN;

D O I：

暂无

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In this review, we focus on the potential that tobacco mosaic virus (TMV) has as a carrier for immunogenic epitopes, and the factors that must be considered in order to bring products based on this platform to the market. Large Scale Biology Corporation developed facile and scaleable methods for manufacture of candidate peptide display vaccines based on TMV. We describe how rational design of., peptide vaccines can improve the manufacturability of particular TMV products. We also discuss downstream processing and purification of the vaccine products, with particular attention to the metrics that a product must attain in order to meet criteria for regulatory approval as injectable biologics.

引用

页码：13 / 31

页数：19

共 50 条

[1] Trastuzumab-binding peptide display by Tobacco mosaic virus
Frolova, Olga Y.
Petrunia, Igor V.
Komarova, Tatiana V.
Kosorukov, Vyacheslav S.
Sheval, Eugene V.
Gleba, Yuri Y.
Dorokhov, Yuri L.
VIROLOGY, 2010, 407 (01) : 7 - 13
[2] Modified Tobacco mosaic virus particles as scaffolds for display of protein antigens for vaccine applications
Smith, Mark L.
Lindbo, John A.
Dillard-Telm, Stephan
Brosio, Paul M.
Lasnik, Amanda B.
McCormick, Alison A.
Nguyen, Long V.
Palmer, Kenneth E.
VIROLOGY, 2006, 348 (02) : 475 - 488
[3] SYSTEMIC PRODUCTION OF FOREIGN PEPTIDES ON THE PARTICLE SURFACE OF TOBACCO MOSAIC-VIRUS
SUGIYAMA, Y
HAMAMOTO, H
TAKEMOTO, S
WATANABE, Y
OKADA, Y
FEBS LETTERS, 1995, 359 (2-3) : 247 - 250
[4] Chimeric Virus-like Particles of Physalis Mottle Virus as Carriers of M2e Peptides of Influenza a Virus
Blokhina, Elena A.
Mardanova, Eugenia S.
Zykova, Anna A.
Shuklina, Marina A.
Stepanova, Liudmila A.
Tsybalova, Liudmila M.
Ravin, Nikolai V.
VIRUSES-BASEL, 2024, 16 (11):
[5] Immunity and Protective Efficacy of a Plant-Based Tobacco Mosaic Virus-like Nanoparticle Vaccine against Influenza a Virus in Mice
Madapong, Adthakorn
Petro-Turnquist, Erika M.
Webby, Richard J.
McCormick, Alison A.
Weaver, Eric A.
VACCINES, 2024, 12 (10)
[6] Adoption of the 2A Ribosomal Skip Principle to Tobacco Mosaic Virus for Peptide Display
Roeder, Juliane
Fischer, Rainer
Commandeur, Ulrich
FRONTIERS IN PLANT SCIENCE, 2017, 8
[7] Burdock fructooligosaccharide induces resistance to tobacco mosaic virus in tobacco seedlings
Wang, Fengde
Feng, Guihua
Chen, Kaoshan
PHYSIOLOGICAL AND MOLECULAR PLANT PATHOLOGY, 2009, 74 (01) : 34 - 40
[8] The physics of tobacco mosaic virus and virus-based devices in biotechnology
Alonso, J. M.
Gorzny, M. L.
Bittner, A. M.
TRENDS IN BIOTECHNOLOGY, 2013, 31 (09) : 530 - 538
[9] Surface modification of tobacco mosaic virus with "Click" chemistry
Bruckman, Michael A.
Kaur, Gagandeep
Lee, L. Andrew
Xie, Fang
Sepulvecla, Jennifer
Breitenkamp, Rebecca
Zhang, Xiongfei
Joralemon, Maisie
Russell, Thomas P.
Emrick, Todd
Wang, Qian
CHEMBIOCHEM, 2008, 9 (04) : 519 - 523
[10] Isolation of Tobacco Mosaic Virus-Binding Peptides for Biotechnology Applications
Chan, Soo Khim
Steinmetz, Nicole F.
CHEMBIOCHEM, 2022, 23 (11)

← 1 2 3 4 5 →