Incidental Memory Encoding Assessed with Signal Detection Theory and Functional Magnetic Resonance Imaging (fMRI)

被引：8

作者：

Clemens, Benjamin ^{[1
,5
]}

Regenbogen, Christina ^{[1
,2
]}

Koch, Kathrin ^{[3
,4
]}

Backes, Volker ^{[1
,5
]}

Romanczuk-Seiferth, Nina ^{[6
]}

Pauly, Katharina ^{[1
]}

Shah, N. Jon ^{[5
,7
,8
]}

Schneider, Frank ^{[1
,5
]}

Habel, Ute ^{[1
,5
]}

Kellermann, Thilo ^{[1
,5
]}

机构：

[1] Rhein Westfal TH Aachen, Fac Med, Dept Psychiat Psychotherapy & Psychosomat, D-52062 Aachen, Germany

[2] Karolinska Inst, Dept Clin Neurosci, Stockholm, Sweden

[3] Tech Univ Munich, Klinikum Rechts Isar, Dept Neuroradiol, D-80290 Munich, Germany

[4] Tech Univ Munich, Klinikum Rechts Isar, TUM Neuroimaging Ctr TUM NIC, D-80290 Munich, Germany

[5] JARA Translat Brain Med, Aachen, Germany

[6] Charite, Dept Psychiat & Psychotherapy, D-13353 Berlin, Germany

[7] Rhein Westfal TH Aachen, Fac Med, Dept Neurol, D-52062 Aachen, Germany

[8] Forschungszentrum Julich, INM 4, D-52425 Julich, Germany

来源：

FRONTIERS IN BEHAVIORAL NEUROSCIENCE | 2015年 / 9卷

关键词：

encoding; facial recognition; fMRI; memory; signal detection theory; MEDIAL TEMPORAL-LOBE; PREDICTS SUBSEQUENT MEMORY; FUSIFORM FACE AREA; BRAIN RESPONSES; EMOTION; SYSTEM; RECOGNITION; CORTEX; METAANALYSIS; NETWORKS;

D O I：

10.3389/fnbeh.2015.00305

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

In functional magnetic resonance imaging (fMRI) studies that apply a "subsequent memory" approach, successful encoding is indicated by increased fMRI activity during the encoding phase for hits vs. misses, in areas underlying memory encoding such as the hippocampal formation. Signal detection theory (SDT) can be used to analyze memory related fMRI activity as a function of the participant's memory trace strength (d'). The goal of the present study was to use SDT to examine the relationship between fMRI activity during incidental encoding and participants' recognition performance. To implement a new approach, post-experimental group assignment into High- or Low Performers (HP or LP) was based on 29 healthy participants' recognition performance, assessed with SDT. The analyses focused on the interaction between the factors group (HP vs. LP) and recognition performance (hits vs. misses). A whole brain analysis revealed increased activation for HP vs. LP during incidental encoding for remembered vs. forgotten items (hits > misses) in the insula/temporo-parietal junction (TPJ) and the fusiform gyrus (FFG). Parameter estimates in these regions exhibited a significant positive correlation with d'. As these brain regions are highly relevant for salience detection (insula), stimulus driven attention (TPJ), and content-specific processing of mnemonic stimuli (FFG), we suggest that HPs' elevated memory performance was associated with enhanced attentional and content-specific sensory processing during the encoding phase. We provide first correlative evidence that encoding related activity in content specific sensory areas and content-independent attention and salience detection areas influences memory performance in a task with incidental encoding of facial stimuli. Based on our findings, we discuss whether the aforementioned group differences in brain activity during incidental encoding might constitute the basis of general differences in memory performance between HP and LP.

引用

页数：13

共 94 条

[1] When less is more: TPJ and default network deactivation during encoding predicts working memory performance [J].