Reply to Pauls et al.: p21 is a master regulator of HIV replication in macrophages through dNTP synthesis block

被引：13

作者：

Allouch, Awatef ^{[1
]}

David, Annie ^{[1
]}

Amie, Sarah M. ^{[2
]}

Lahouassa, Hichem ^{[3
]}

Chartier, Loic ^{[4
]}

Margottin-Goguet, Florence ^{[3
,5
,6
]}

Barre-Sinoussi, Francoise ^{[1
,7
]}

Kim, Baek ^{[2
,8
]}

Saez-Cirion, Asier ^{[1
]}

Pancino, Gianfranco ^{[1
,7
]}

机构：

[1] Inst Pasteur, Dept Virol, Unite Regulat Infect Retrovirales, F-75015 Paris, France

[2] Emory Univ, Dept Pediat, Ctr Drug Discovery, Atlanta, GA 30322 USA

[3] INSERM, Inst Cochin, U1016, F-75014 Paris, France

[4] Inst Pasteur, Unite Rech & Expertise Epidemiol Malad Emergentes, F-75015 Paris, France

[5] CNRS, UMR 8104, F-75014 Paris, France

[6] Univ Paris 05, F-75006 Paris, France

[7] Univ Paris 06, INSERM, F-75013 Paris, France

[8] Kyung Hee Univ, Coll Pharm, Seoul 130701, South Korea

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 2014年 / 111卷 / 14期

关键词：

PHOSPHORYLATION; RESTRICTION; SAMHD1;

D O I：

10.1073/pnas.1322699111

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：E1325 / E1326

页数：2

共 6 条

[1] p21-mediated RNR2 repression restricts HIV-1 replication in macrophages by inhibiting dNTP biosynthesis pathway [J].

Allouch, Awatef ;

David, Annie ;

Amie, Sarah M. ;

Lahouassa, Hichem ;

Chartier, Loic ;

Margottin-Goguet, Florence ;

Barre-Sinoussi, Franoise ;

Kim, Baek ;

Saez-Cirion, Asier ;

Pancino, Gianfranco .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2013, 110 (42) :E3997-E4006

[2] The CDK Inhibitor p21Cip1/WAF1 Is Induced by FcγR Activation and Restricts the Replication of Human Immunodeficiency Virus Type 1 and Related Primate Lentiviruses in Human Macrophages [J].

Bergamaschi, Anna ;

David, Annie ;

Le Rouzie, Erwann ;

Nisole, Sebastien ;

Barre-Sinoussi, Francoise ;

Pancino, Gianfranco .

JOURNAL OF VIROLOGY, 2009, 83 (23) :12253-12265

[3] Phosphorylation of SAMHD1 by Cyclin A2/CDK1 Regulates Its Restriction Activity toward HIV-1 [J].

Cribier, Alexandra ;

Descours, Benjamin ;

Chaves Valadao, Ana Luiza ;

Laguette, Nadine ;

Benkirane, Monsef .

CELL REPORTS, 2013, 3 (04) :1036-1043

[4] p21 regulates the HIV-1 restriction factor SAMHD1 [J].

Pauls, Eduardo ;

Ruiz, Alba ;

Riveira-Munoz, Eva ;

Permanyer, Marc ;

Badia, Roger ;

Clotet, Bonaventura ;

Keppler, Oliver T. ;

Ballana, Ester ;

Este, Jose A. .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2014, 111 (14) :E1322-E1324

[5] Restriction of Virus Infection but Not Catalytic dNTPase Activity Is Regulated by Phosphorylation of SAMHD1 [J].

Welbourn, Sarah ;

Dutta, Sucharita M. ;

Semmes, O. John ;

Strebel, Klaus .

JOURNAL OF VIROLOGY, 2013, 87 (21) :11516-11524

[6] The Retroviral Restriction Ability of SAMHD1, but Not Its Deoxynucleotide Triphosphohydrolase Activity, Is Regulated by Phosphorylation [J].

White, Tommy E. ;

Brandariz-Nunez, Alberto ;

Valle-Casuso, Jose Carlos ;

Amie, Sarah ;

Laura Anh Nguyen ;

Kim, Baek ;

Tuzova, Marina ;

Diaz-Griffero, Felipe .

CELL HOST & MICROBE, 2013, 13 (04) :441-451

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