Molecular docking analysis of beta-catenin with compounds derived from Lycopersicon esculentum

被引:1
作者
Selvaraj, Jayaraman [1 ]
Vishnupriya, Veeraraghavan [1 ]
Sardar, Hussain [2 ]
Balakrishna, Janardhana Papayya [3 ]
Rex, Josephine [4 ]
Mohan, Surapaneni Krishna [4 ,5 ]
Vijayalakshmi, Periyasamy [6 ]
Ponnulakshmi, Rajagopal [7 ]
机构
[1] Saveetha Univ, Saveetha Dent Coll & Hosp, Saveetha Inst Med & Tech Sci, Dept Biochem, Chennai 600077, Tamil Nadu, India
[2] Govt Sci Coll, Dept Biotechnol, Chitradurga 577501, Karnataka, India
[3] Stellixir Biotech Pvt Ltd, Dept Stem Cell Biol, 5-31,2nd Floor,10th Main Rd, Bangalore 560058, Karnataka, India
[4] Panimalar Med Coll Hosp & Res Inst, Dept Biochem, Chennai 600123, Tamil Nadu, India
[5] Panimalar Med Coll Hosp & Res Inst, Dept Clin Skills & Simulat, Chennai 600123, Tamil Nadu, India
[6] Holy Cross Coll Autonomous, PG & Res Dept Biotechnol & Bioinformat, Trichy 620002, Tamil Nadu, India
[7] Meenakshi Acad Higher Educ & Res Deemedto Be Univ, Cent Res Lab, Chennai 600078, Tamil Nadu, India
关键词
Colon Cancer; Lycopersicon esculentum; Beta-catenin; Molecular docking; COLORECTAL-CANCER; INHIBITION; MUTATIONS; GENES; FAP;
D O I
10.6026/97320630016801
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Beta-catenin is linked with colorectal cancer (CRC). Therefore, it is of interest to design and develop novel compounds to combat CRC. Hence, we document compounds (chlorogenic acid, gallic add, protocatechuic acid, quercetin and vanillic add) from Lycopersicon esculentum with optimal binding features for further consideration.
引用
收藏
页码:801 / 806
页数:6
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