Pyridylhydroxybutyl, pyridyloxobutyl and methyl DNA phosphate adduct formation in rats treated chronically with enantiomers of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol

被引：0

作者：

Ma, Bin ^{[1
]}

Zarth, Adam ^{[1
]}

Carlson, Erik ^{[1
]}

Villalta, Peter ^{[1
]}

Upadhyaya, Pramod ^{[1
]}

Stepanov, Irina ^{[1
]}

Hecht, Stephen ^{[1
]}

机构：

[1] Univ Minnesota, Masonic Canc Ctr, Minneapolis, MN USA

来源：

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2017年 / 254卷

关键词：

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

引用

页数：1

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[21] Formation of formaldehyde adducts in the reactions of DNA and deoxyribonucleosides with α-acetates of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), and N-nitrosodimethylamine (NDMA) [J].

Cheng, Guang ;

Wang, Mingyao ;

Upadhyaya, Pramod ;

Villalta, Peter W. ;

Hecht, Stephen S. .

CHEMICAL RESEARCH IN TOXICOLOGY, 2008, 21 (03) :746-751

[22] Genetic variability in the metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) to 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) [J].

Ter-Minassian, Monica ;

Asomaning, Kofi ;

Zhao, Yang ;

Chen, Feng ;

Su, Li ;

Carmella, Steven G. ;

Lin, Xihong ;

Hecht, Stephen S. ;

Christiani, David C. .

INTERNATIONAL JOURNAL OF CANCER, 2012, 130 (06) :1338-1346

[23] Synthesis and in vivo quantitation of 2′-deoxyadenosine adducts resulting from bioactivation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol [J].

Carlson, Erik ;

Upadhyaya, Pramod ;

Hecht, Stephen .

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2017, 254

[24] Effects of long term dietary phenethyl isothiocyanate on the microsomal metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in F344 rats [J].

Staretz, ME ;

Koenig, LA ;

Hecht, SS .

CARCINOGENESIS, 1997, 18 (09) :1715-1722

[25] Disposition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in bile duct-cannulated rats: Stereoselective metabolism and tissue distribution [J].

Wu, Z ;

Upadhyaya, P ;

Carmella, SG ;

Hecht, SS ;

Zimmerman, CL .

CARCINOGENESIS, 2002, 23 (01) :171-179

[26] Absolute configuration of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol formed metabolically from 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (vol 18, pg 1851, 1997) [J].

Hecht, SS ;

Spratt, TE ;

Trushin, N .

CARCINOGENESIS, 2000, 21 (04) :850-850

[27] Identification of N6-[4-oxo and 4-hydroxy-4-(3-pyridyl)but-1-yl]deoxyadenosine in lung tissues of F-344 rats treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of its metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol [J].

Upadhyaya, Pramod ;

Balbo, Silvia ;

Hecht, Stephen S. .

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2014, 248

[28] Analysis of phosphate adducts in hepatic and pulmonary DNA of rats treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone [J].

Ma, Bin ;

Villalta, Peter ;

Zarth, Adam ;

Kotandeniya, Delshanee ;

Upadhyaya, Pramod ;

Stepanov, Irina ;

Hecht, Stephen .

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2015, 250

[29] Comparative Levels of O6-Methylguanine, Pyridyloxobutyl-, and Pyridylhydroxybutyl-DNA Adducts in Lung and Liver of Rats Treated Chronically with the Tobacco-Specific Carcinogen 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone [J].

Upadhyaya, Pramod ;

Lindgren, Bruce R. ;

Hecht, Stephen S. .

DRUG METABOLISM AND DISPOSITION, 2009, 37 (06) :1147-1151

[30] Combined Analysis of the Tobacco Metabolites Cotinine and 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol in Human Urine [J].

Kotandeniya, Delshanee ;

Carmella, Steven G. ;

Ming, Xun ;

Murphy, Sharon E. ;

Hecht, Stephen S. .

ANALYTICAL CHEMISTRY, 2015, 87 (03) :1514-1517

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