Isolation and identification of dihydrochrysanolide and its 1-epimer from Chrysanthemum coronarium L.

被引：20
|
作者：
Lee, KD
Yang, MS
Ha, TJ
Park, KM
Park, KH [1 ]
机构：
[1] Gyeongsang Natl Univ, Div Appl Life Sci, Dept Agr Chem, Chinju 660701, South Korea
[2] Gyeongsang Natl Univ, Res Inst Nat Sci, Chinju 660701, South Korea
来源：
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 2002年 / 66卷 / 04期
关键词：
Chrysanthemum coronarium L; sesquiterpene lactone; dihydrochrysanolide; 1-epi-dihydrochrysanolide; cytotoxic activity;
D O I：
10.1271/bbb.66.862
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A new sesquiterpene lactone (1) was isolated with known dihydrochrysanolide derivatives (2 and 3) from the flowers of Chrysanthemum coronarium L., and their structures were identified by spectroscopic data. The stereochemistry of the epimers (1 and 2) was determined from NOESY data and an X-ray crystallographic analysis. The isolated compounds (1-3) were examined for their cytotoxic activity against such human cell lines as A549, PC-3 and HCT-15.
引用
收藏
页码：862 / 865
页数：4
相关论文
共 50 条
  • [21] A Correlation between Antioxidant Activity and Metabolite Release during the Blanching of Chrysanthemum coronarium L.
    Kim, Jiyoung
    Choi, Jung Nam
    Ku, Kang Mo
    Kang, Daejung
    Kim, Jong Sang
    Park, Jung Han Yoon
    Lee, Choong Hwan
    BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2011, 75 (04) : 674 - 680
  • [22] Glycerides from the Aerial Parts of Garland (Chrysanthemum coronarium L.) and Their Inhibitory Effects on ACAT, DGAT, FPTase, and β-Secretase
    Song, Myoung-Chong
    Yang, Hye-Joung
    Cho, Jin-Gyeong
    Chung, In-Sik
    Kwon, Byoung-Mog
    Kim, Dae-Keun
    Baek, Nam-In
    FOOD SCIENCE AND BIOTECHNOLOGY, 2009, 18 (01) : 95 - 102
  • [23] Heterocyclic compounds from Chrysanthemum coronarium L. and their inhibitory activity on hACAT-1, hACAT-2, and LDL-oxidation
    Song, Myoung-Chong
    Yang, Hye-Joung
    Jeong, Tae-Sook
    Kim, Kyong-Tai
    Baek, Nam-In
    ARCHIVES OF PHARMACAL RESEARCH, 2008, 31 (05) : 573 - 578
  • [24] Heterocyclic compounds from Chrysanthemum coronarium L. and their inhibitory activity on hACAT-1, hACAT-2, and LDL-oxidation
    Myoung-Chong Song
    Hye-Joung Yang
    Tae-Sook Jeong
    Kyong-Tai Kim
    Nam-In Baek
    Archives of Pharmacal Research, 2008, 31 : 573 - 578
  • [25] High frequency shoot regeneration from leaf disc explants of garland chrysanthemum (Chrysanthemum coronarium L) in vitro
    Lee, T
    Huang, MEE
    Pua, EC
    PLANT SCIENCE, 1997, 126 (02) : 219 - 226
  • [26] Ensiling forage garland (Chrysanthemum coronarium L.) at two stages of maturity and at different wilting levels
    Valente, ME
    Borreani, G
    Caredda, D
    Cavallarin, L
    Sulas, L
    ANIMAL FEED SCIENCE AND TECHNOLOGY, 2003, 108 (1-4) : 181 - 190
  • [27] Isolation and Structural Characterization of a New Neutral Polysaccharide from Chrysanthemum indicum L.
    Jin Hong-Ying
    Shi Song-Shan
    Wang Shun-Chun
    Wang Zheng-Tao
    Hu Zhi-Bi
    CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 2012, 33 (04): : 755 - 760
  • [28] POLYACETYLENE COMPOUNDS .171. SYNTHESIS OF THIOETHERS ISOLATED FROM CHRYSANTHEMUM CORONARIUM L
    BOHLMANN, F
    SCHUBER, J
    CHEMISCHE BERICHTE-RECUEIL, 1969, 102 (12): : 4209 - &
  • [29] Optimization of the Extraction Technology of Flavonoids from Chrysanthemum coronarium L.by Microwave Method
    ZHANG Jin-feng1*
    2.Department of Basic Education
    Medicinal Plant, 2012, (02) : 57 - 60
  • [30] The effect of high temperature stress on the occurrence of dead heart before and during flower bud differentiation in garland chrysanthemum (Chrysanthemum coronarium L.)
    Yamasaki, M
    Tsuji, H
    JOURNAL OF THE JAPANESE SOCIETY FOR HORTICULTURAL SCIENCE, 2001, 70 (04): : 496 - 500
12345