Caenorhabditis elegans:: a model genetic host to study Pseudomonas aeruginosa pathogenesis

被引:120
作者
Tan, MW
Ausubel, FM
机构
[1] Harvard Univ, Sch Med, Dept Genet, Boston, MA 02114 USA
[2] Massachusetts Gen Hosp, Dept Biol Mol, Boston, MA 02114 USA
关键词
D O I
10.1016/S1369-5274(99)00047-8
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
In the past year, a Caenorhabditis elegans-Pseudomonas aeruginosa pathogenesis model has been developed to facilitate the systematic dissection of both host and pathogen genes involved in pathogenic interactions. Analysis of the P. aeruginosa-C. elegans interaction should shed light on the larger question of how organisms interact at the molecular level in antagonistic relationships.
引用
收藏
页码:29 / 34
页数:6
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