Magnesium and Human Health: Perspectives and Research Directions

被引：288
作者：
Al Alawi, Abdullah M. [1 ,2 ]
Majoni, Sandawana William [1 ,3 ,4 ]
Falhammar, Henrik [1 ,3 ,5 ,6 ]
机构：
[1] Royal Darwin Hosp, Div Med, Darwin, NT, Australia
[2] Sultan Qaboos Univ Hosp, Dept Med, Muscat, Oman
[3] Menzies Sch Hlth Res, Darwin, NT, Australia
[4] Flinders Univ S Australia, Sch Med, Northern Terr Med Program, Darwin, NT, Australia
[5] Karolinska Univ Hosp, Dept Endocrinol Metab & Diabet, Stockholm, Sweden
[6] Karolinska Inst, Dept Mol Med & Surg, Stockholm, Sweden
来源：
INTERNATIONAL JOURNAL OF ENDOCRINOLOGY | 2018年 / 2018卷
关键词：
BONE-MINERAL DENSITY; OBSTRUCTIVE PULMONARY-DISEASE; TYPE-1; DIABETIC-PATIENTS; IN-HOSPITAL MORTALITY; INTENSIVE-CARE-UNIT; SERUM MAGNESIUM; DIETARY MAGNESIUM; DOUBLE-BLIND; INSULIN-RESISTANCE; ACUTE EXACERBATION;
D O I：
10.1155/2018/9041694
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Magnesium is the fourth most abundant cation in the body. It has several functions in the human body including its role as a cofactor for more than 300 enzymatic reactions. Several studies have shown that hypomagnesemia is a common electrolyte derangement in clinical setting especially in patients admitted to intensive care unit where it has been found to be associated with increase mortality and hospital stay. Hypomagnesemia can be caused by a wide range of inherited and acquired diseases. It can also be a side effect of several medications. Many studies have reported that reduced levels of magnesium are associated with a wide range of chronic diseases. Magnesium can play important therapeutic and preventive role in several conditions such as diabetes, osteoporosis, bronchial asthma, preeclampsia, migraine, and cardiovascular diseases. This review is aimed at comprehensively collating the current available published evidence and clinical correlates of magnesium disorders.
引用
收藏
页数：17
相关论文
共 183 条
[1]   Magnesium sulfate affords protection against oxidative damage during severe preeclampsia [J].
Abad, C. ;
Vargas, F. R. ;
Zoltan, T. ;
Proverbio, T. ;
Pinero, S. ;
Proverbio, E. ;
Marin, R. .
PLACENTA, 2015, 36 (02) :179-185
[2]   Magnesium as an Effective Adjunct Therapy for Drug Resistant Seizures [J].
Abdelmalik, Peter A. ;
Politzer, Nina ;
Carlen, Peter L. .
CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES, 2012, 39 (03) :323-327
[3]   Association between intakes of magnesium, potassium, and calcium and risk of stroke: 2 cohorts of US women and updated meta-analyses [J].
Adebamowo, Sally N. ;
Spiegelman, Donna ;
Willett, Walter C. ;
Rexrode, Kathryn M. .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 2015, 101 (06) :1269-1277
[4]  
Agus ZS, 1999, J AM SOC NEPHROL, V10, P1616
[5]   BONE MAGNESIUM POOLS IN UREMIA [J].
ALFREY, AC ;
MILLER, NL .
JOURNAL OF CLINICAL INVESTIGATION, 1973, 52 (12) :3019-3027
[6]   Association between Low Serum Magnesium Level and Major Adverse Cardiac Events in Patients Treated with Drug-Eluting Stents for Acute Myocardial Infarction [J].
An, Guipeng ;
Du, Zhongqi ;
Meng, Xiao ;
Guo, Tao ;
Shang, Rui ;
Li, Jifu ;
An, Fengshuang ;
Li, Wenjing ;
Zhang, Cheng .
PLOS ONE, 2014, 9 (06)
[7]   The association of serum magnesium and mortality outcomes in heart failure patients A systematic review and meta-analysis [J].
Angkananard, Teeranan ;
Anothaisintawee, Thunyarat ;
Eursiriwan, Sudarat ;
Gorelik, Oleg ;
McEvoy, Mark ;
Attia, John ;
Thakkinstian, Ammarin .
MEDICINE, 2016, 95 (50)
[8]  
[Anonymous], 2017, NUTRIENTS
[9]  
[Anonymous], 2007, ELECTROLYTE BLOOD PR, DOI DOI 10.5049/EBP.2007.5.2.126
[10]   MAGNESIUM-DEFICIENCY IN CRITICALLY ILL PATIENTS [J].
ARNOLD, A ;
TOVEY, J ;
MANGAT, P ;
PENNY, W ;
JACOBS, S .
ANAESTHESIA, 1995, 50 (03) :203-205
12345678910