Microfluidic cell culture

被引：287

作者：

Mehling, Matthias ^{[1
]}

Tay, Savas ^{[1
]}

机构：

[1] Swiss Fed Inst Technol, Dept Biosyst Sci & Engn, Zurich, Switzerland

来源：

CURRENT OPINION IN BIOTECHNOLOGY | 2014年 / 25卷

基金：

瑞士国家科学基金会;

关键词：

ON-A-CHIP; PLATFORM; REGENERATION; VARIABILITY; INTEGRATION; GENERATION; GRADIENTS; RESPONSES; CYTOKINE; DELIVERY;

D O I：

10.1016/j.copbio.2013.10.005

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Microfluidic techniques allow precise control of fluids and particles at the nanoliter scale and facilitate simultaneous manipulation and analysis of cultured cells, starting from a single cell to larger populations and to intact tissues. The use of integrated microfluidic devices has considerably advanced the fields of quantitative and systems biology. In this review, we survey the recent developments in microfluidic cell culture, and discuss not only the advantages but also limitations of using such systems, and give an outlook on potential future developments.

引用

页码：95 / 102

页数：8

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