Capillary monoliths for the analysis of nucleic acids by high-performance liquid chromatography-electrospray ionization mass spectrometry

被引：99
作者：
Oberacher, H
Huber, CG
机构：
[1] Univ Saarland, D-66041 Saarbrucken, Germany
[2] Univ Innsbruck, Inst Analyt Chem & Radiochem, A-6020 Innsbruck, Austria
来源：
TRAC-TRENDS IN ANALYTICAL CHEMISTRY | 2002年 / 21卷 / 03期
基金：
奥地利科学基金会;
关键词：
nucleic acids; ohgonucleotides; ion-pair reversed-phase liquid chromatography; monolithic capillary columns; electrospray ionization-mass spectrometry (ESI-MS);
D O I：
10.1016/S0165-9936(02)00304-7
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Monolithic capillary columns prepared by copolymerization of styrene and divinylbenzene inside a 200 mum i.d. fused silica capillary allow the rapid and highly efficient separation of single- and double-stranded DNA by ion-pair reversed-phase high-performance liquid chromatography. Hyphenation to electrospray ionization-mass spectrometry can be readily achieved. (C) 2002 Published by Elsevier Science B.V. All rights reserved.
引用
收藏
页码：166 / 174
页数：9
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