Death of the motor neurones in amyotrophic lateral sclerosis: suicide or murder?

被引:3
作者
Pettmann, Brigitte [1 ]
Raoul, Cedric
Haase, Georg
机构
[1] Univ Mediterranee, CNRS, IBDM, F-13288 Marseille 09, France
[2] Ecole Polytech Fed Lausanne, Integrat Biosci Inst, SV IBI LEN, CH-1015 Lausanne, Switzerland
[3] Univ Mediterranee, INSERM, Inst Neurobiol Mediterranee, INMED,Equipe Avenir, F-13273 Marseille 09, France
来源
M S-MEDECINE SCIENCES | 2006年 / 22卷 / 11期
关键词
D O I
10.1051/medsci/20062211923
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
引用
收藏
页码:923 / 925
页数:3
相关论文
共 10 条
  • [1] Activated p38MAPK is a novel component of the intracellular inclusions found in human amyotrophic lateral sclerosis and mutant SOD1 Transgenic mice
    Bendotti, C
    Atzori, C
    Piva, R
    Tortarolo, M
    Strong, MJ
    DeBiasi, S
    Migheli, A
    [J]. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 2004, 63 (02) : 113 - 119
  • [2] Onset and progression in inherited ALS determined by motor neurons and microglia
    Boillee, Severine
    Yamanaka, Koji
    Lobsiger, Christian S.
    Copeland, Neal G.
    Jenkins, Nancy A.
    Kassiotis, George
    Kollias, George
    Cleveland, Don W.
    [J]. SCIENCE, 2006, 312 (5778) : 1389 - 1392
  • [3] Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice
    Clement, AM
    Nguyen, MD
    Roberts, EA
    Garcia, ML
    Boillée, S
    Rule, M
    McMahon, AP
    Doucette, W
    Siwek, D
    Ferrante, RJ
    Brown, RH
    Julien, JP
    Goldstein, LSB
    Cleveland, DW
    [J]. SCIENCE, 2003, 302 (5642) : 113 - 117
  • [4] From Charcot to Lou Gehrig: Deciphering selective motor neuron death in ALS
    Cleveland, DW
    Rothstein, JD
    [J]. NATURE REVIEWS NEUROSCIENCE, 2001, 2 (11) : 806 - 819
  • [5] Restricted expression of G86R Cu/Zn superoxide dismutase in astrocytes results in astrocytosis but does not cause motoneuron degeneration
    Gong, YH
    Parsadanian, AS
    Andreeva, A
    Snider, WD
    Elliott, JL
    [J]. JOURNAL OF NEUROSCIENCE, 2000, 20 (02) : 660 - 665
  • [6] Accumulation of SOD1 mutants in postnatal motoneurons does not cause motoneuron pathology or motoneuron disease
    Lino, MM
    Schneider, C
    Caroni, P
    [J]. JOURNAL OF NEUROSCIENCE, 2002, 22 (12) : 4825 - 4832
  • [7] Motoneuron death triggered by a specific pathway downstream of Fas:: Potentiation by ALS-linked SOD1 mutations
    Raoul, C
    Estévez, AG
    Nishimune, H
    Cleveland, DW
    deLapeyrière, O
    Henderson, CE
    Haase, G
    Pettmann, B
    [J]. NEURON, 2002, 35 (06) : 1067 - 1083
  • [8] Chronic activation in presymptornatic amyotrophic lateral sclerosis (ALS) mice of a feedback loop involving Fas, Daxx, and FasL
    Raoul, C
    Buhler, E
    Sadeghi, C
    Jacquier, A
    Aebischer, P
    Pettmann, B
    Haase, G
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2006, 103 (15) : 6007 - 6012
  • [9] Programmed cell death of embryonic motoneurons triggered through the Fas death receptor
    Raoul, C
    Henderson, CE
    Pettmann, B
    [J]. JOURNAL OF CELL BIOLOGY, 1999, 147 (05) : 1049 - 1061
  • [10] Microglia as potential contributors to motor neuron injury in amyotrophic lateral sclerosis
    Sargsyan, SA
    Monk, PN
    Shaw, PJ
    [J]. GLIA, 2005, 51 (04) : 241 - 253