Advances in predicting the prognosis of hepatocellular carcinoma recipients after liver transplantation

被引:9
作者
Wang, Li-ying [1 ]
Zheng, Shu-sen [2 ]
机构
[1] Shaoxing Second Hosp, Dept Ultrasound, Shaoxing 312000, Peoples R China
[2] Zhejiang Univ, Key Lab Combined Multiorgan Transplantat, Div Hepatobiliary & Pancreat Surg, Minist Hlth,Dept Surg,Affiliated Hosp 1,Sch Med, Hangzhou 310003, Zhejiang, Peoples R China
基金
中国国家自然科学基金;
关键词
Hepatocellular carcinoma; Liver transplantation; Recurrence; Risk factor; Prognosis; SERUM ALPHA-FETOPROTEIN; REFINED SELECTION CRITERIA; SINGLE-CENTER EXPERIENCE; MILAN CRITERIA; CHILD-PUGH; TUMOR SIZE; CURATIVE RESECTION; HANGZHOU CRITERIA; UP-TO-7; CRITERIA; RISK-FACTORS;
D O I
10.1631/jzus.B1700156
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Hepatocellular carcinoma (HCC) is one of the most prevalent malignant tumors worldwide. Liver transplantation (LT) is known as a curative and therapeutic modality. However, the survival rates of recipients after LT are still not good enough because of tumor recurrence. To improve the survival rates of recipients after LT, identifying predictive factors for prognosis after LT and establishing a model assessing prognosis are very important to HCC patients. There has recently been a lot of clinical and basic research on recurrence and prognosis after LT. Progress has been made, especially in selection criteria for LT recipients and risk factors for predicting prognosis after LT. Hangzhou criteria, in line with China's high current incidence rate of primary liver, are first proposed by Chinese scholars of LT, and are accepted world-wide, and make an important contribution to the development of LT.
引用
收藏
页码:497 / 504
页数:8
相关论文
共 53 条
[41]   HBV DNA and HBsAg Levels as Risk Predictors of Early and Late Recurrence after Curative Resection of HBV-related Hepatocellular Carcinoma [J].
Sohn, Won ;
Paik, Yong-Han ;
Kim, Jong Man ;
Kwon, Choon Hyuk ;
Joh, Jae Won ;
Cho, Ju Yeon ;
Gwak, Geum-Youn ;
Choi, Moon Seok ;
Lee, Joon Hyeok ;
Koh, Kwang Cheol ;
Paik, Seung Woon ;
Yoo, Byung Chul .
ANNALS OF SURGICAL ONCOLOGY, 2014, 21 (07) :2429-2435
[42]   Reassessing Selection Criteria Prior to Liver Transplantation for Hepatocellular Carcinoma Utilizing the Scientific Registry of Transplant Recipients Database [J].
Toso, Christian ;
Asthana, Sonal ;
Bigam, David L. ;
Shapiro, A. M. James ;
Kneteman, Norman M. .
HEPATOLOGY, 2009, 49 (03) :832-838
[43]   Risk Factors of Hepatocellular Carcinoma Recurrence After Liver Transplantation: Accuracy of the Alpha-Fetoprotein Model in a Single-Center Experience [J].
Varona, M. A. ;
Soriano, A. ;
Aguirre-Jaime, A. ;
Garrido, S. ;
Oton, E. ;
Diaz, D. ;
Portero, J. ;
Bravo, P. ;
Barrera, M. A. ;
Perera, A. .
TRANSPLANTATION PROCEEDINGS, 2015, 47 (01) :84-89
[44]   Impact of locoregional therapy and alpha-fetoprotein on outcomes in transplantation for liver cancer: a UNOS Region 6 pooled analysis [J].
Wong, Linda L. ;
Naugler, Willscott E. ;
Schwartz, Jonathan ;
Scott, David L. ;
Bhattacharya, Renuka ;
Reyes, Jorge ;
Orloff, Susan L. .
CLINICAL TRANSPLANTATION, 2013, 27 (01) :E72-E79
[45]   Liver transplantation for hepatocellular carcinoma beyond the Milan criteria [J].
Xu, Xiao ;
Lu, Di ;
Ling, Qi ;
Wei, Xuyong ;
Wu, Jian ;
Zhou, Lin ;
Yan, Sheng ;
Wu, Liming ;
Geng, Lei ;
Ke, Qinghong ;
Gao, Feng ;
Tu, Zhenhua ;
Wang, Weilin ;
Zhang, Min ;
Shen, Yan ;
Xie, Haiyang ;
Jiang, Wenshi ;
Wang, Haibo ;
Zheng, Shusen .
GUT, 2016, 65 (06) :1035-1041
[46]   The Value of Serum α-Fetoprotein in Predicting Tumor Recurrence After Liver Transplantation for Hepatocellular Carcinoma [J].
Xu, Xiao ;
Ke, Qing-Hong ;
Shao, Zhe-Xin ;
Wu, Jian ;
Chen, Jun ;
Zhou, Lin ;
Zheng, Shu-Sen .
DIGESTIVE DISEASES AND SCIENCES, 2009, 54 (02) :385-388
[47]   A revised scoring system utilizing serum alphafetoprotein levels to expand candidates for living donor transplantation in hepatocellular carcinoma [J].
Yang, Sung Hoon ;
Suh, Kyung-Suk ;
Lee, Hae Won ;
Cho, Eung-Ho ;
Cho, Jai Young ;
Cho, Yong Beom ;
Kim, In Hwan ;
Yi, Nam-Joon ;
Lee, Kuhn Uk .
SURGERY, 2007, 141 (05) :598-609
[48]   Liver transplantation for hepatocellular carcinoma: Validation of the UCSF-Expanded criteria based on preoperative imaging [J].
Yao, F. Y. ;
Xiao, L. ;
Bass, N. M. ;
Kerlan, R. ;
Ascher, N. L. ;
Roberts, J. P. .
AMERICAN JOURNAL OF TRANSPLANTATION, 2007, 7 (11) :2587-2596
[49]   Downstaging of hepatocellular cancer before liver transplant: Long-term outcome compared to tumors within Milan criteria [J].
Yao, Francis Y. ;
Mehta, Neil ;
Flemming, Jennifer ;
Dodge, Jennifer ;
Hameed, Bilal ;
Fix, Oren ;
Hirose, Ryutaro ;
Fidelman, Nicholas ;
Kerlan, Robert K., Jr. ;
Roberts, John P. .
HEPATOLOGY, 2015, 61 (06) :1968-1977
[50]   Liver transplantation for hepatocellular carcinoma: Expansion of the tumor size limits does not adversely impact survival [J].
Yao, FY ;
Ferrell, L ;
Bass, NM ;
Watson, JJ ;
Bacchetti, P ;
Venook, A ;
Ascher, NL ;
Roberts, JP .
HEPATOLOGY, 2001, 33 (06) :1394-1403