Survival and complications of total hip arthroplasty using third-generation dual-mobility cups with non-cross-linked polyethylene liners in patients younger than 55 years

Background: In younger patients, total hip prostheses are subjected to wide motion ranges and wear-inducing forces. Dual-mobility cups (DMCs) are effective in decreasing the risk of dislocation. However, wear and osteolysis have been reported with first-generation DMCs. These complications have not been assessed in younger patients managed with third-generation DMCs associated with a lower risk of intra-prosthetic dislocation (IPD). We therefore designed a retrospective study of patients younger than 55 years at THA with third-generation DMCs. Our objectives were to evaluate (1) the complication rate, and (2) the survival rate. Hypothesis: The rate of complications of THA with third-generation DMCs in patients younger than 55 years of age is comparable to that in the general population of THA patients. Material and methods: This retrospective study included 79 consecutive patients (91 hips) who had total hip arthroplasty (THA) between 2007 and 2012. We included all patients younger than 55 years who underwent primary THA with a third-generation DMC and a liner made of non-cross-linked polyethylene. The patients were evaluated clinically and radiologically. Results: Mean follow-up was 9.8 years (range: 2-13 years). At last follow-up, no patient had experienced prosthetic dislocation or IPD. Aseptic and septic cup loosening each occurred in 1 patient. In all, 7 (7.7%) patients required revision surgery with exchange of at least one component (cup loosening, n = 2; neck fracture with a short stem fixed to the neck, n = 1; peri-prosthetic femoral fracture, n = 1; infection, n = 1; and femoral-stem loosening, n = 2). Peri-acetabular osteolysis developed in 2 (2.2%) hips. Cup survival to aseptic loosening was 98.9% (95% confidence interval, 97%-100%) and survival to revision for any reason except infection was 95.6% (95% confidence interval, 82%-100%). Discussion: In patients younger than 55 years, third-generation DMCs were associated with absence of prosthetic dislocation, absence of IPD, and a low revision rate for cup loosening, in the medium term. These implants therefore constitute a viable treatment option in younger patients requiring THA. Level of evidence: IV, retrospective study. (c) 2022 Elsevier Masson SAS. All rights reserved.