Antioxidant Vitamins as Oxidative Stress Markers in Rat Plasma After Physical Exercise - a Short Report

被引:2
作者
Wawrzyniak, Agata [1 ]
Hamulka, Jadwiga [1 ]
Drywien, Malgorzata [1 ]
Gornicka, Magdalena [1 ]
Pierzynowska, Jolanta [1 ]
Wojtas, Malwina [1 ]
Gajewska, Malgorzata [2 ]
Frackiewicz, Joanna [1 ]
Gronowska-Senger, Anna [1 ]
机构
[1] Warsaw Univ Life Sci WULS SGGW, Dept Human Nutr, Chair Nutr Assessment, PL-02776 Warsaw, Poland
[2] Warsaw Univ Life Sci WULS SGGW, Dept Physiol Sci, Chair Biochem, PL-02776 Warsaw, Poland
关键词
beta-carotene; retinol; vitamin E; vitamin C; exercise; rats; BETA-CAROTENE; ASCORBIC-ACID; EXHAUSTIVE EXERCISE; ALPHA-TOCOPHEROL; SUPPLEMENTATION;
D O I
10.2478/pjfns-2013-0025
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
The aim of the study was to verify the hypothesis that p carotene, vitamin E, vitamin C administered individually or in combination may differently modify their levels in blood plasma being also markers of the oxidative stress. Male Wistar rats were supplemented antioxidants per os (alpha-to-copherol - 2 mg/d, ascorbic acid - 12 mg/d, beta-carotene - 1 mg/d), both individually or in combination of 2 or 3, for 14 days. During experiment, half of the animals in each group (n=8) were subjected to treadmill exercise for 15 min at the speed of 20 m/min, to induce oxidative stress. Vitamins in rat plasma were assessed by the high performance liquid chromatography (HPLC). Results suggest that vitamin E and C supplemented simultaneously may provide some benefit during physical exercise. The significant influence of administered alpha-tocopherol acetate and physical exercise on the level of alpha-tocopherol in the plasma was observed. Thus only the concentration of alpha-tocopherol in blood may be treated as a marker of oxidative stress.
引用
收藏
页码:277 / 281
页数:5
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