Catalytic Asymmetric Synthesis of Chiral Benzofuranones

被引：68
|
作者：
Li, Yao [1 ]
Li, Xin [1 ]
Cheng, Jin-Pei [1 ]
机构：
[1] Nankai Univ, Dept Chem, State Key Lab Elementoorgan Chem, Collaborat Innovat Ctr Chem Sci & Engn, Tianjin 300071, Peoples R China
来源：
ADVANCED SYNTHESIS & CATALYSIS | 2014年 / 356卷 / 06期
基金：
中国国家自然科学基金;
关键词：
asymmetric catalysis; benzofuranones; organocatalysis; stereoselectivity; MICHAEL ADDITION-REACTIONS; 3-SUBSTITUTED BENZOFURAN-2(3H)-ONES; ENANTIOSELECTIVE SYNTHESIS; FACILE SYNTHESIS; MBH CARBONATES; ORAL TREATMENT; DIELS-ALDER; SPIRO; GRISEOFULVIN; CONSTRUCTION;
D O I：
10.1002/adsc.201301038
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
The chiral benzofuranone structural motif is a prominent feature in many natural products, which exhibit a broad range of biological and pharmaceutical activities. In the past few years, a survey of chiral benzofuranone derivatives based on asymmetric catalysis reveals an increasing number of papers, which reflects the latest achievements to facilitate the synthesis of sufficient quantities of related compounds as potential medicinal agents and biological probes. Recent advances in this area are summarized and classified according to the structure of the starting substrate.
引用
收藏
页码：1172 / 1198
页数：27
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