Herd Protection against Meningococcal Disease through Vaccination

被引：23

作者：

Clark, Stephen A. ^{[1
]}

Borrow, Ray ^{[1
]}

机构：

[1] Publ Hlth England, Meningococcal Reference Unit, Natl Infect Serv, Manchester M13 9WL, Lancs, England

来源：

MICROORGANISMS | 2020年 / 8卷 / 11期

关键词：

Neisseria meningitidis; meningococcal infection; meningococcal incidence; invasive meningococcal disease (IMD); IMD epidemiology; meningococcal vaccine; meningococcal vaccination; AFRICAN MENINGITIS BELT; MUCOSAL IMMUNE-RESPONSES; C CONJUGATE VACCINE; SEROGROUP-B; GROUP-A; POLYSACCHARIDE VACCINES; NEISSERIA-MENINGITIDIS; CAPSULAR POLYSACCHARIDE; EPIDEMIOLOGIC IMPACT; UNIVERSITY-STUDENTS;

D O I：

10.3390/microorganisms8111675

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Reduction in the transmission of Neisseria meningitidis within a population results in fewer invasive disease cases. Vaccination with meningococcal vaccines composed of high weight capsular polysaccharide without carrier proteins has minimal effect against carriage or the acquisition of carriage. Conjugate vaccines, however, elicit an enhanced immune response which serves to reduce carriage acquisition and hinder onwards transmission. Since the 1990s, several meningococcal conjugate vaccines have been developed and, when used in age groups associated with higher carriage, they have been shown to provide indirect protection to unvaccinated cohorts. This herd protective effect is important in enhancing the efficiency and impact of vaccination. Studies are ongoing to assess the effect of protein-based group B vaccines on carriage; however, current data cast doubt on their ability to reduce transmission.

引用

页码：1 / 16

页数：16

共 97 条

[1] An epidemiological review of changes in meningococcal biology during the last 100 years [J].

Abio, Anne ;

Neal, Keith R. ;

Beck, Charles R. .

PATHOGENS AND GLOBAL HEALTH, 2013, 107 (07) :373-380

[2] The Global Meningococcal Initiative meeting on prevention of meningococcal disease worldwide: Epidemiology, surveillance, hypervirulent strains, antibiotic resistance and high-risk populations [J].

Acevedo, Reinaldo ;

Bai, Xilian ;

Borrow, Ray ;

Caugant, Dominique A. ;

Carlos, Josefina ;

Ceyhan, Mehmet ;

Christensen, Hannah ;

Climent, Yanet ;

De Wals, Philippe ;

Dinleyici, Ener Cagri ;

Echaniz-Aviles, Gabriela ;

Hakawi, Ahmed ;

Kamiya, Hajime ;

Karachaliou, Andromachi ;

Lucidarme, Jay ;

Meiring, Susan ;

Mironov, Konstantin ;

Safadi, Marco A. P. ;

Shao, Zhujun ;

Smith, Vinny ;

Steffen, Robert ;

Stenmark, Bianca ;

Taha, Muhamed-Kheir ;

Trotter, Caroline ;

Vazquez, Julio A. ;

Zhu, Bingqing .

EXPERT REVIEW OF VACCINES, 2019, 18 (01) :15-30

[3] The Diversity of Meningococcal Carriage Across the African Meningitis Belt and the Impact of Vaccination With a Group A Meningococcal Conjugate Vaccine [J].

Ali, Oumer ;

Aseffa, Abraham ;

Bedru, Ahmed ;

Lema, Tsehaynesh ;

Moti, Tesfaye ;

Tekletsion, Yenenesh ;

Worku, Alemayehu ;

Xabher, Haimanot Guebre ;

Yamuah, Lawrence ;

Boukary, Rahamatou Moustapha ;

Collard , Jean-Marc ;

Dano, Ibrahim Dan ;

Habiboulaye, Ibrahim ;

Issaka, Bassira ;

Jusot, Jean-Francois ;

Ousmane, Sani ;

Rabe, Issoufa ;

Daugla , Doumagoum Moto ;

Gami, Jean Pierre ;

Gamougam, Kadidja ;

Mbainadji, Lodoum ;

Naibei, Nathan ;

Narbe, Maxime ;

Toralta, Jacques ;

Berthe, Abdoulaye ;

Diallo, Kanny ;

Keita, Mahamadou ;

Onwuchekwa, Uma ;

Sow , Samba O. ;

Tamboura, Boubou ;

Traore, Awa ;

Toure, Alou ;

Clark, Tom ;

Mayer, Leonard ;

Amodu, Mary ;

Beida, Omeiza ;

Gadzama, Galadima ;

Omotara , Babatunji ;

Sambo, Zailani ;

Yahya, Shuaibu ;

Chandramohan, Daniel ;

Greenwood , Brian M. ;

Hassan-King, Musa ;

Manigart, Olivier ;

Nascimento, Maria ;

Stuart, James M. ;

Woukeu, Arouna ;

Basta, Nicole E. ;

Bai, Xilian ;

Borrow, Ray .

JOURNAL OF INFECTIOUS DISEASES, 2015, 212 (08) :1298-1307

[4] Salivary and Serum Antibody Response Against Neisseria meningitidis After Vaccination With Conjugate Polysaccharide Vaccines in Ethiopian Volunteers [J].

Barnes, G. K. ;

Workalemahu, B. ;

Kristiansen, P. A. ;

Beyene, D. ;

Merdekios, B. ;

Fissiha, P. ;

Aseffa, A. ;

Caugant, D. A. ;

Naess, L. M. .

SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 2016, 84 (02) :118-129

[5] IMMUNOGLOBULIN-M AND IMMUNOGLOBULIN-G ANTIBODY-RESPONSES AND PERSISTENCE OF THESE ANTIBODIES IN ADULTS AFTER VACCINATION WITH A COMBINED MENINGOCOCCAL GROUP-A AND GROUP-C POLYSACCHARIDE VACCINE [J].

BEUVERY, EC ;

LEUSSINK, AB ;

VANDELFT, RW ;

TIESJEMA, RH ;

NAGEL, J .

INFECTION AND IMMUNITY, 1982, 37 (02) :579-585

[6] A Decade of Herd Protection After Introduction of Meningococcal Serogroup C Conjugate Vaccination [J].

Bijlsma, Merijn W. ;

Brouwer, Matthijs C. ;

Spanjaard, Lodewijk ;

van de Beek, Diederik ;

van der Ende, Arie .

CLINICAL INFECTIOUS DISEASES, 2014, 59 (09) :1216-1221

[7] HERD-IMMUNITY AND THE MENINGOCOCCAL VACCINE TRIAL IN NORWAY [J].

BJUNE, G .

LANCET, 1992, 340 (8814) :315-315

[8] Recent changes in the epidemiology of Neisseria meningitidis serogroup W across the world, current vaccination policy choices and possible future strategies [J].

Booy, Robert ;

Gentile, Angela ;

Nissen, Michael ;

Whelan, Jane ;

Abitbol, Veronique .

HUMAN VACCINES & IMMUNOTHERAPEUTICS, 2019, 15 (02) :470-480

[9] Salivary antibodies following parenteral immunization of infants with a meningococcal serogroup A and C conjugated vaccine [J].

Borrow, R ;

Fox, AJ ;

Cartwright, K ;

Begg, NT ;

Jones, DM .

EPIDEMIOLOGY AND INFECTION, 1999, 123 (02) :201-208

[10] The Global Meningococcal Initiative: global epidemiology, the impact of vaccines on meningococcal disease and the importance of herd protection [J].

Borrow, Ray ;

Alarcon, Pedro ;

Carlos, Josefina ;

Caugant, Dominique A. ;

Christensen, Hannah ;

Debbag, Roberto ;

De Wals, Philippe ;

Echaniz-Aviles, Gabriela ;

Findlow, Jamie ;

Head, Chris ;

Holt, Daphne ;

Kamiya, Hajime ;

Saha, Samir K. ;

Sidorenko, Sergey ;

Taha, Muhamed-Kheir ;

Trotter, Caroline ;

Vazquez Moreno, Julio A. ;

von Gottberg, Anne ;

Safadi, Marco A. P. .

EXPERT REVIEW OF VACCINES, 2017, 16 (04) :313-328

← 1 2 3 4 5 6 7 8 9 10 →