Advances in PHAs Production

被引:25
作者
Amache, Rana [1 ]
Sukan, Artun [1 ]
Safari, Maryam [1 ]
Roy, Ipsita [1 ]
Keshavarz, Tajalli [1 ]
机构
[1] Univ Westminster, Sch Life Sci, Appl Biotechnol Res Grp, London W1R 8AL, England
来源
ICHEAP-11: 11TH INTERNATIONAL CONFERENCE ON CHEMICAL AND PROCESS ENGINEERING, PTS 1-4 | 2013年 / 32卷
关键词
FED-BATCH CULTURE; RECOMBINANT ESCHERICHIA-COLI; POLY(3-HYDROXYBUTYRATE) PRODUCTION; POLY(BETA-HYDROXYBUTYRATE) PRODUCTION; POLYHYDROXYALKANOATES; WASTE; GLYCEROL; GLUCOSE; STRAIN; STATE;
D O I
10.3303/CET1332156
中图分类号
TQ [化学工业];
学科分类号
0817 ;
摘要
Polyhydroxyalkanoates (PHAs) are biological polyesters produced through microbial fermentation processes. They have attracted attention as an alternative source to petro-chemically derived plastics as they are biodegradable, renewable, biocompatible and environmentally friendly. However, a notable limitation for their bulk production is the producer microbes' low yield and productivity which leads to high production costs. Intensive research is being carried out at all production steps including strain selection and improvement, media development, fermentation and bioreactor design to downstream unit operations in order to improve the overall process efficiency and performance. This review article concentrates on the current state of PHA production, with particular emphasis on media composition focusing on waste material as substrate. Bioreactor types and culturing methods will also be explored.
引用
收藏
页码:931 / 936
页数:6
相关论文
共 36 条
  • [1] Production of poly(3-hydroxybutyrate) by fed-batch culture of recombinant Escherichia coli with a highly concentrated whey solution
    Ahn, WS
    Park, SJ
    Lee, SY
    [J]. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2000, 66 (08) : 3624 - 3627
  • [2] Strategies for the development of a side stream process for polyhydroxyalkanoate (PHA) production from sugar cane molasses
    Albuquerque, M. G. E.
    Eiroa, M.
    Torres, C.
    Nunes, B. R.
    Reis, M. A. M.
    [J]. JOURNAL OF BIOTECHNOLOGY, 2007, 130 (04) : 411 - 421
  • [3] Continuous production of poly([R]-3-hydroxybutyrate) by Cupriavidus necator in a multistage bioreactor cascade
    Atlic, Aid
    Koller, Martin
    Scherzer, Dietrich
    Kutschera, Christoph
    Grillo-Fernandes, Elizabeth
    Horvat, Predrag
    Chiellini, Emo
    Braunegg, Gerhart
    [J]. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2011, 91 (02) : 295 - 304
  • [4] Production of polyhydroxyalkanoates (PHAs) from waste materials and by-products by submerged and solid-state fermentation
    Castilho, Leda R.
    Mitchel, David A.
    Freire, Denise M. G.
    [J]. BIORESOURCE TECHNOLOGY, 2009, 100 (23) : 5996 - 6009
  • [5] Poly(3-hydroxybutyrate) production by Cupriavidus necator using waste glycerol
    Cavalheiro, Joao M. B. T.
    de Almeida, M. Catarina M. D.
    Grandfils, Christian
    da Fonseca, M. M. R.
    [J]. PROCESS BIOCHEMISTRY, 2009, 44 (05) : 509 - 515
  • [6] Chakraborty P., 2012, BIOMED RES
  • [7] Chandel A. K., 2012, J CHEM TECHNOLOGY BI
  • [8] Du C., 2012, CURRENT CHEM BIOL, V6, P14, DOI [10.2174/2212796811206010014, DOI 10.2174/2212796811206010014]
  • [9] Production of poly(3-hydroxybutyrate) from waste potato starch
    Haas, Richard
    Jin, Bo
    Zepf, Florian Tobias
    [J]. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2008, 72 (01) : 253 - 256
  • [10] Poly(3-Hydroxybutyrate) Production from Glycerol by Zobellella denitrificans MW1 via High-Cell-Density Fed-Batch Fermentation and Simplified Solvent Extraction
    Ibrahim, Mohammad H. A.
    Steinbuechel, Alexander
    [J]. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2009, 75 (19) : 6222 - 6231